Prakt. lékáren. 2007; 3(6): 267-269

Restless Legs Syndrome - Syndrom neklidných nohou

Mgr. Kateřina Ošlejšková-Vašutová
Lékárna Slunce, Zlín

Syndrom neklidných nohou (RLS) je neurologické onemocnění doprovázené poruchami spánku. Nejčastěji se léčí dopaminergními léčivy (L-DOPA) a agonisty dopaminu (pergolid, pramipexol, ropinirol). Vzhledem k jejich nežádoucím účinkům a pravděpodobnosti výskytu dlouhodobě trvajících komplikací se hledají možnosti alternativní nondopaminergní léčby (např. benzodiazepiny nebo gabapentin). Největší význam pro léčbu RLS bude mít ovšem objevení molekulárně biologické příčiny RLS, kdy bude možné terapii zacílit zcela přesně.

Keywords: syndrom neklidných nohou, L-DOPA

Published: January 20, 2008  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Ošlejšková-Vašutová K. Restless Legs Syndrome - Syndrom neklidných nohou. Praktické lékárenství. 2007;3(6):267-269.
Download citation

References

  1. Allen RP, Picchietti D, Hening WA, Trenkwalder C, Walters AS, Montplaisir J. Restless legs syndrome: diagnostic criteria, special considerations and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health. Sleep Med 2003, 4: 101-119. Go to original source... Go to PubMed...
  2. Aukerman, M, Aukerman D, Bayard M, Tudiver F, Thorp L, Bailey B.: Excercise and Restless Legs Syndrome: A Randomized Controlled Trial. Journal of the American Board of Family Medicine, 2006, 19: 487-493. Go to original source... Go to PubMed...
  3. Garcia - Borreguero D, Larrosa O, de la Llave Y, Verger K, Masramon X, Hernandez G. Treatment of restless legs syndrome with gabapentin: a double-blind, cross-over study. Neurology, 59/10, 2002: 1573-1579. Go to original source... Go to PubMed...
  4. Pelletier G, Lorrain D, Montplaisir J. Sensory and motor components of the restless legs syndrom. Neurology 1992, 42: 1663-1666. Go to original source... Go to PubMed...
  5. Phillips B, Young T, Finn, L, Asher K, Hening W.A, Purvis CH. Epidemiology of Restless Legs Symptoms in Adults. Arch Intern Med, 2000, 160: 2137-2141. Go to original source... Go to PubMed...
  6. Pretl M.: Syndrom neklidných končetin. Psychiat. pro Praxi, 2003, 2: 57-59.
  7. Sun ER, Chen CA, Ho G, Earley CJ, Allen RP. Iron and the restless legs syndrome. Sleep 1998, 21: 371-377. Go to original source... Go to PubMed...
  8. Šonka K. Syndrom neklidných nohou. Maxdorf Jesenius. Praha 2006. S. 75.
  9. Trenkwalder C., Walters AS, Hening W. Periodic limb movements and restless legs syndrome. Neurol Clin 1996, 14: 629-650. Go to original source... Go to PubMed...




Pharmacy for Practice

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.