Prakt. lékáren. 2009; 5(3): 114-117
During past decades pharmacotherapy of arterial hypertension underwent significant development. New guidelines for the management
of arterial hypertension defined several categories according to the blood pressure levels and blood pressure therapy goals too.
Pharmacotherapy of hypertension is guided either by blood pressure level, or the presence of associated clinical condition, the severity
of target organ damage and the total cardiovascular risk. The efficacy of the treatment on cardiovascular mortality and morbidity is based
on the effect on blood pressure lowering. Effective decrease of blood pressure is provided by: thiazide diuretics, beta-blockers, calcium
channel blockers, angiotensin-converting enzyme inhibitors and angiotensin receptor blockers. These drugs represent the treatment
of choice either for monotherapy, or for the combination. Choice of the treatment drug group depends on the type of the associated
clinical condition.
Published: May 1, 2009 Show citation