Prakt. lékáren. 2009; 5(5): 219-222

Optimal dosage of paracetamol for treating pain and fever

prof. MUDr. Miloslav Kršiak DrSc1, prof. MUDr. Jan Švihovec, DrSc2, prof. Igor Zupanets, MD, PhD3, prof. MUDr. Milan Kriška DrSc4
1 Ústav farmakologie 3. LF UK, Praha
2 Ústav farmakologie, 2. LF Univerzity Karlovy, Praha
3 Dpt. of Clinical Pharmacology, National University of Pharmacy, Kharkov, Ukraine
4 Ústav farmakológie LF UK Bratislava

The generally stated and accepted single analgesic dose of paracetamol by mouth is 10–15 mg/kg (see below). The SPCs and PILs of medications

containing 500 mg of paracetamol in adults recommend the dose of 1–2 tablets. Thus, in individuals with a body weight over

50 kg, underdosage occurs with a dose of 500 mg, which may cause insufficient efficacy. The optimal dosage of paracetamol should be

defined based on the patient's body weight.

Keywords: acetaminophen, dosage, body weight, pain, fever.

Published: August 1, 2009  Show citation

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Kršiak M, Švihovec J, Zupanets I, Kriška M. Optimal dosage of paracetamol for treating pain and fever. Praktické lékárenství. 2009;5(5):219-222.
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    References

    1. Kobzová, et al. The 6th nationwide anthropological survey of children and adolescent in the Czech Republic in 2001. Centr Eur J Public Health 2004; 12: 126-130.
    2. Kunešová, et al. Životní styl a obezita: děti 13-17 let.
    3. http://www.rustovyhormon.cz/percentilove-rustovegrafy.

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