Prakt. lékáren. 2011; 7(3): 111-114

Contribution to questions of pharmacological treatment in the elderly

MUDr.David Suchý, Ph.D., MUDr.Milan Hromádka, Ph.D.
1 Oddělení klinické farmakologie, Fakultní nemocnice v Plzni
2 I. interní klinika, Fakultní nemocnice v Plzni

Pharmacotherapy in the elderly is complicated by multifactorial issues, including age-related physiologic changes, the presence of

multiple chronic disease states, functional changes in mental and physical abilities, and decrease of patienťs ability to comply with

recommended therapy. Adverse drug reactions and interactions are more common than in the general l population. Geriatric clinical

syndromes can be induced or exacerbated by prescribed and OTC pharmaceuticals. Pharmacodynamic and pharmacokinetic changes

may alter response to a given medication resulting in increased risc of adverse reactions. Pharmacotherapy in elderly requires specific

approach and awareness in indicating medication to senior patiens.

compliance.

Keywords: pharmacotherapy in the elderly, polymorbidity, polypraharmacy, pharmacokinetics, pharmacodynamics, adverse reactions,

Published: June 1, 2011  Show citation

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Suchý D, Hromádka M. Contribution to questions of pharmacological treatment in the elderly. Praktické lékárenství. 2011;7(3):111-114.
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