Prakt. lékáren. 2012; 8(1): 18-21

News in the treatment of HIV

Marcela Krečmerová
Ústav organické chemie a biochemie Akademie věd České republiky, v. v. i.

Thirty years after identification of AIDS (acquired immunodeficiency syndrome) as a new clinical syndrome with uncertain prospects of

the treatment, the current pharmaceutical industry offers 31 single or combined medicinal drugs with different mechanisms of action.

Development of the new anti-HIV compounds is still being continued, with respect to the ability of the virus to make resistance towards

the current treatment and significant side effects of antiretrovirals. Since 1996, the standard therapy is HAART (highly active antiretroviral

therapy) or more recently, cART (combination antiretroviral therapy). Intensive investigation is also carried out in the field of preventive

effects of microbicides containing tenofovir.

Keywords: HIV, AIDS, cART, HAART, tenofovir, reverse transcriptase, HIV protease, mikrobicides

Published: March 1, 2012  Show citation

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Krečmerová M. News in the treatment of HIV. Praktické lékárenství. 2012;8(1):18-21.
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