Prakt. lékáren. 2013; 9(2): 59-63

Local therapy of psoriasis

Zuzana Nevoralová
Kožní oddělení nemocnice v Jihlavě

Psoriasis is a chronic, inflammatory hyperproliferative disease of the skin, scalp, nails and joints. It belongs to a group of papulosquamosus

skin disorders and is presented by a variety of clinical presentations. Basic treatment is a local therapy, another treatment options

are phototherapy and systemic therapy. In this article, local therapy is described. It is a ground option for mild and moderate psoriasis,

a complementary one for a severy psoriasis. A first line local therapy includes topical corticosteroids and D3 derivates; tars, ichtamol,

cignolin, baths and local imunomodulators are also useful. Many completely new therapeutics are developed and proved.

Keywords: psoriasis, local therapy, corticosteroids, vitamin D3 derivates

Published: April 15, 2013  Show citation

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Nevoralová Z. Local therapy of psoriasis. Praktické lékárenství. 2013;9(2):59-63.
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References

  1. Benáková N. Terapie obecně. In: Benáková N, Ettler K, Štork, J, Vašků V. Psoriáza nejen pro praxi. Praha/Kroměříž: Triton 2007: 59-69.
  2. Ettler K. Fototerapie. In: Benáková N, Ettler K, Štork J, Vašků V. Psoriáza nejen pro praxi. Praha/Kroměříž: Triton 2007: 102-112.
  3. Archier E, Devaux S, Castela E, et al. EfficacyofPsoralen UV-A therapy vs. Narrowband UV-B therapy in chronicplaque psoriasis: a systematicliteraturereview. J Eur AcadDermatolVenereol 2012; 26(Suppl.3): 11-21. Go to original source... Go to PubMed...
  4. Benáková N. Celková terapie. In: Benáková N: Terapie obecně. In: Benáková N, Ettler K, Štork J, Vašků V. Psoriáza nejen pro praxi. Praha/Kroměříž: Triton 2007: 117-131, 148-152.
  5. Pathriana D, Ormerod AD, Saiag P, et al. European S3-Guidelines on thesystemictreatmentof psoriasis. J Eur AcadDermatolVenereol 2009; 23(Suppl.2): 23, 27.
  6. Berend MAM, Sadek J, Kerkhof van de PCM, et al. Liver injury in long-term methotrexatetreatment in psoriasis isrelativelyinfrequent. DermatolTherapy 2006. Go to original source...
  7. Dostál C, Pavelka K, Saudek F, et al. Ciclosporinum. Remedia 2005; 1: 33-52.
  8. Benáková N, Štork J, et al. Léčba psoriázy biologiky. Konsenzuální doporučené postupy České dermatovenerologické společnosti ČLS JEP 2006. Čes-slov Derm 2006, 81(4): 1-11.
  9. Menter A, Korman NJ, Elmets CA, et al. Guidelinesofcarefor management of psoriasis and psoriasis arthritis. Section 6. Guidelinesofcarefor management of psoriasis and psoriasis arthritis: Case-basedpresentations and evidence-basedconclusions. J AmAcadDermatol 2011; 65: 134-174.
  10. Nast A, Boehncke WH, Mrowietz U, et al. S3-Guidelines on thetreatmentof psoriasis vulgaris. Update 2001. JDDG 2011; 9(Suppl.2): S1-S95. Go to original source...
  11. Cetkovská P, Kojanová M. Česká doporučení k biologické léčbě závažné chronické ložiskové psoriázy. Čes-slov Derm 2012, 87(1): I-XXII.
  12. Chiricozzi A, Chimenti S. EffectiveTopicalAgents and EmergingPerspectives in theTreatmentof Psoriasis. Expert RevDermatol 2012; 7(3): 283-293. Go to original source...
  13. Murray PJ. The JAK-STAT signaling pathway: input and output integration. J. Immunol 2007; 178(5): 2623-2629. Go to original source... Go to PubMed...
  14. Subramaniam SV, Cooper RS, Adunyah SE. Evidence for the involvement of JAK/STAT pathway in the signaling mechanism of interleukin-17.BiochemBiophys Res Commun 1999; 262(1): 14-19. Go to original source... Go to PubMed...
  15. Kwatra SG, Dabade TS, Gustafson CJ, et al. JAK inhibitors in psoriasis: a promisingnewtreatment modality. J DrugsDermatol 2012; 11(8): 913-918.
  16. Psoriasis Treatment: What´s in the Future? www.webmd.com/skin.
  17. Papp KA, Gulliver W, Lynde CHW, et al. TheFutureof Psoriasis care. In: Papp KA, Gulliver W, Lynde CHW, et al. CanadianGuidelinesforthe Management ofPlaque Psoriasis. 2009; 1stedn: 89-92.
  18. Pánková R. Psychoterapie v ambulantní praxi. Lékařské listy 2003; 17: 14-16.
  19. Benáková N. Psoriáza v otázkách a odpovědích. Praha: Triton 2005: 128.




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