Prakt. lékáren. 2013; 9(3): 120-123

Fundamentals of prevention and treatment of kidney diseases

Romana Ryšavá

Klinika nefrologie 1. LF UK a VFN Praha

Chronic kidney diseases affect nearly a tenth of our population and are becoming not only a medical issue, but also a social-economic

problem. The best measures taken to prevent the development of advanced stages of disease include the implementation of screening

programs to find patients with an existing renal injury or those at a high risk. Basic tests include measurement of serum creatinine

and glomerular filtration rate, urine sediment analysis and proteinuria or microalbuminuria testing. Measures that can significantly

slow down (or even stop) the progression of chronic nephropathies are treatment with angiotensin-converting enzyme inhibitors or

angiotensin II AT1 receptor antagonists, consistent hypertension management with achievement of normotension (< 140/90 mmHg),

and reduction of proteinuria below 0.5 g/day. Additional measures, such as reducing dietary protein intake, treatment of dyslipidemia,

no smoking, weight reduction, or effective glycemic control in diabetics, may also significantly contribute to reducing the risk of

developing kidney disease.

Keywords: chronic kidney disease, microalbuminuria, proteinuria, glomerular filtration rate, low-protein diet

Published: July 15, 2013  Show citation