Prakt. lékáren. 2014; 10(3): 90-94
as seen by a pharmacist
Nonsteroidal anti-inflammatory drugs are encountered by pharmacists in their practice on a daily basis. These drugs, however, have
a number of adverse effects and a relatively large interaction potential. Gastrointestinal tract injury, hepatopathy, nephropathy,
and increased cardiovascular risk are among the most serious adverse effects. Drug interactions usually potentiate these risks. The article
deals with particular adverse effects of nonsteroidal anti-inflammatory drugs and also describes the quantitative difference in the rates
of these risks among the individual agents from the class of nonsteroidal anti-inflammatory drugs. The most common clinically significant
drug interactions of nonsteroidal anti-inflammatory drugs are presented in a table. Two case reports are included to demonstrate
the management of the risks of nonsteroidal anti-inflammatory drugs.
Published: June 1, 2014 Show citation