Prakt. lékáren. 2015; 11(5): 170-173

Drug Dosing Considerations for Patients With chronic kidney disease

Drahomíra Stará
Institut klinické a experimentální medicíny Praha

Dosage adjustment is an essential standard of care of patients with chronic kidney disease. Although main aspect for dosage adjustment

is decreased renal elimination, it is necessary to understand potential impact in the case of change in drug absorption, distribution, non-

-renal elimination and pharmacodynamics. Another significant part of dosage adjustment is assessment of glomerular filtration rate.

It is important for this reason to distinguish among particular methods of estimation of glomerular filtration rate or creatinine clearance

and in the case of crucial differences to choose the most suitable one for individual patient.

Keywords: chronic kidney disease, pharmacokinetics, drug dosage adjustments, clinical pharmacy

Published: October 1, 2015  Show citation

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Stará D. Drug Dosing Considerations for Patients With chronic kidney disease. Praktické lékárenství. 2015;11(5):170-173.
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