Prakt. lékáren. 2018; 14(1): 8-10 | DOI: 10.36290/lek.2018.002

Trends in pharmacotherapy for elderly patients

Katarína Bielaková, Hana Matějovská Kubešová
Klinika interní, geriatrie a praktického lékařství FN Brno Bohunice, Masarykova univerzita

The elderly are the largest consumers of prescribed medications. Prescribing for the elderly is complicated by a variety of factors.The presence of multiple chronic conditions and multiple medications leads to potentially complex drug-drug and drug-diseaseinteractions. Several tools and algorithms are available to aid clinicians in prescribing of adequate treatment. Good clinical assessment,an understanding of the patient´s overall condition and individual treatment goals remain pivotal to provide high qualitycare and to decrease adverse drug reactions occurence.

Keywords: geriatric patient, adverse drug reactions, polypragmasy, medication adherence, compliance, screening tools

Published: March 24, 2018  Show citation

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Bielaková K, Matějovská Kubešová H. Trends in pharmacotherapy for elderly patients. Praktické lékárenství. 2018;14(1):8-10. doi: 10.36290/lek.2018.002.
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References

  1. ÚZIS. Zdravotnická ročenka 2015. Dostupný na: http://www.uzis.cz/node/7693
  2. Lehnert T, Heider D, Leicht H, et al. Review: health care utilization and costs of elderly persons with multiple chronic conditions. Med Care Res Rev 2011; 68: 387-420. Go to original source... Go to PubMed...
  3. Franceschi M, Scarcelli C, Niro V, et al. Prevalence, clinical features and avoidability of adverse drug reactions as cause of admission to a geriatric unit: a prospective study of 1756 patients. Drug Saf 2008; 31: 545-556. Go to original source... Go to PubMed...
  4. Fialová D. Specifické rysy geriatrické farmakoterapie (I). Změna terapeutické hodnoty léků ve stáří. Praha: Karolinum 2008. 92 s.
  5. Vlček J, Fialová D, a kol. Klinická farmacie I. 1 vyd. Praha: Grada. 2010, 368 s.
  6. Davies EC, Green CF, Mottram DR, et al. Adverse drug reactions in hospitals: a narrative review. Curr Drug Saf 2007; 2: 79-87. Go to original source... Go to PubMed...
  7. Pirmohamed M, James S, Meakin S, et al. Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients. BMJ 2004; 329: 15-19. Go to original source... Go to PubMed...
  8. Wester K, Jönsson AK, Spigset O, et al. Incidence of fatal adverse drug reactions: a population based study. Br J Clin Pharmacol 2008; 65: 573-579. Go to original source... Go to PubMed...
  9. Moore N, Lecointre D, Noblet C, et al. Frequency and cost of serious adverse drug reactions in a department of general medicine. Br J Clin Pharmacol 1998; 45: 301-308. Go to original source... Go to PubMed...
  10. Pedrós C, Quintana B, Rebolledo M, Porta N, Vallano A, Arnau JM. Prevalence, risk factors and main features of adverse drug reactions leading to hospital admission. Eur J Clin Pharmacol 2014; 70(3): 361-367. Go to original source... Go to PubMed...
  11. Parameswaran N, Chalmers L, Bereznicki BJ, et al. Adverse Drug Reaction-Related Hospitalizations in Elderly Australians: A Prospective Cross-Sectional Study in Two Tasmanian Hospitals. Drug Saf 2017; 40(7): 597-606. Go to original source... Go to PubMed...
  12. Wiliams B, Chang A, et al. Current Diagnosis & Treatment: Geriatrics, 2nd ed. 2014: 582 s.
  13. Franceschi M, Scarcelli C, Niro V, et al. Prevalence, clinical features and avoidability of adverse drug reactions as cause of admission to a geriatric unit: a prospective study of 1756 patients. Drug Saf 2008; 31: 545-556. Go to original source... Go to PubMed...
  14. De Paepe P, Petrovic M, Outtier L, et al. Drug interactions and adverse drug reactions in the older patients admitted to the emergency department. Acta Clin Belg 2013; 68: 15-21. Go to original source... Go to PubMed...
  15. Topinková E, Fialová D, Býma S, a kol. Racionální farmakoterapie geriatrických pacientů. Doporučené postupy pro praktické lékaře, 2014. Dostupné z: http://www.svl.cz/files/files/Doporucene-postupy-od-2013/DP-Geriatrie-2014.pdf
  16. Beers MH, Ouslander JG, Rollingher I, et al. Explicit criteria for determining inappropriate medication use in nursing home residents. Arch Intern Med 1991; 151: 1825-1832. Go to original source...
  17. Steinman MA, Beizer JL, DuBeau CE, et al. How to Use the American Geriatrics Society 2015 Beers Criteria-A Guide for Patients, Clinicians, Health Systems, and Payors. J Am Geriatr Soc 2015; 63(12): e1-e7. Go to original source... Go to PubMed...
  18. O'Mahony D, O'Sullivan D, Byrne S, et al. STOPP/START criteria for potentially inappropriate prescribing in older people: Version 2. Age Ageing 2015; 44: 213-218. Go to original source... Go to PubMed...
  19. Fialová D, Topinková E, Ballóková A, Matějovská-Kubešová H. Expertní konsenzus ČR 2012 v oblasti léčiv a lékových postupů potenciálně nevhodných ve stáří. Vhodnost volby léčiv a dávkovacích schémat u geriatrických pacientů (Oddíl I.), interakce lék-nemoc ve stáří (Oddíl II.). Klinická farmakologie a farmacie 2013; 27(1):




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