Prakt. lékáren. 2018; 14(2): 56-62 [Interní Med. 2018; 20(2): 74-80]

Modern aspects of allergic rhinitis

Irena Krčmová, Jakub Novosad

Ústav klinické imunologie a alergologie, Fakultní nemocnice Hradec Králové

Allergic diseases are seen as systemic diseases with organ symptoms. Allergic rhinitis is defined as a group of nasal symptoms,arising from an underlying IgE-mediated inflammation following exposure of the nasal mucosa to allergens. The basic feature ofallergic rhinitis is a persistent eosinophilic inflammation accompanied by typical clinical manifestations. Allergic rhinitis developson the basis of numerous environmental factors in a genetically predisposed individual. The symptoms of rhinitis may be spontaneouslyreversible or resolve following treatment. The management of allergic rhinitis involves patient education, eliminationof allergens, pharmacotherapy, and specific allergen immunotherapy. Sublingual tablet dosage form of allergen immunotherapy(grass pollens, house dust mites) is a modern alternative to subcutaneous treatment. This treatment reduces the severity ofallergy symptoms, lowers the risk of developing new allergic sensitizations, and prevents the development of clinical asthma inpatients treated for allergic rhinitis.

Keywords: allergic rhinitis, pharmacotherapy, allergen immunotherapy

Published: June 20, 2018  Show citation