Prakt. Lékáren. 2018; 14(1e) [Med. praxi. 2017;14(4):193-195]

Beta-lactam allergy today

MUDr. Lenka Sedláčková
Oddělení klinické biochemie, hematologie a imunologie, Centrum alergologie a klinické imunologie,
Nemocnice Na Homolce, Praha

Allergy to penicillin and other beta-lactams is the most frequently reported drug allergy. It is usually not questioned due to its known riskof severe and even fatal anaphylaxis. However, the diagnosis is often based on various symptoms in temporal connection with antibioticuse only, and is not checked any more. A complete allergy workup including a provocation test confirms a true allergy only in a smallnumber of patients. It can rid a patient of a false diagnosis and of a needless limitation of therapeutic possibilities. Its wider application inpractice is very desirable.

Keywords: penicillin, beta-lactam antibiotics, allergy, hypersensitivity

Published: March 24, 2018  Show citation

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Sedláčková L. Beta-lactam allergy today. Praktické lékárenství. 2018;14(E-verze 1/18):.
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