Prakt. lékáren. 2019; 15(2): 74-76 | DOI: 10.36290/lek.2019.038

Specifics of neonatal pharmacotherapy

Andrea Staníková
Neonatologické oddělení FN Brno

Pharmacologic therapies have made a significant contribution to reducing both mortality and morbidity in neonates. A particular
problem in neonates is the off-label use of medicines. This reflects the lack of scientific evidence and availability of appropriate
licensed formulations in neonatology. Unfortunately, for most drugs there is a lack of oral formulations for neonates. Use of
magistral formulations is therefore part of daily neonatal practice. This article discusses the developmental changes in neonatal
period and the most frequent problems in neonatal clinical pharmacology.

Keywords: neonatology, clinical pharmacology, pharmacokinetic, pharmacodynamic, magistral preparation

Received: January 28, 2019; Accepted: February 11, 2019; Prepublished online: February 11, 2019; Published: June 20, 2019  Show citation

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Staníková A. Specifics of neonatal pharmacotherapy. Praktické lékárenství. 2019;15(2):74-76. doi: 10.36290/lek.2019.038.
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