Prakt. lékáren. 2019; 15(2): 111-116 | DOI: 10.36290/lek.2019.021
Glucocorticoids are the strongest known anti-inflammatory agents. They are used broadly in various medical disciplines. The present article is aimed at the dermatological formulation. It deals with the aspects affecting absorption of topical corticosteroids from the vehicles as well as with the classification of individual agents based on effect strength, and provides notes on the therapeutic index of selected compounds. In terms of magistral preparation, galenic properties of topical corticosteroids are presented, as are the possibilities of formulating substances into a compounded drug in general terms. Also presented are the factors affecting stability. The text contains examples of particular formulations used in the practice.
Published: June 20, 2019 Show citation