Prakt. lékáren. 2022; 18(1): E38-E55 [Med. praxi. 2021;18(4):266-273]

Herbal preparations and their drug interactions in routine outpatient practice

Alice Sychrová
Ústav přírodních léčiv, Farmaceutická fakulta, Masarykova univerzita, Brno

More and more patients are choosing self-medication procedures, including phytotherapy whose popularity is constantly growing. Patients mistakenly believe that the use of herbal preparations is completely safe. In addition to the possible toxicity of the plant itself, there is also a risk of drug interactions. The ones most at risk are people over 65 years old, patients with polypharmacy, polymorbidity, or with severe chronic diseases. Recent scientific studies have highlighted the risks associated with the co-administration of grapefruit, ginkgo, licorice, and St. John's wort with many drugs. These interactions may have fatal consequences, so a general practitioner's competence in this issue is highly required. His or her professional focus is on the care of patients with various health problems and complications; accordingly, this paper presents clinically relevant interactions of herbal preparations with drugs from different pharmacotherapeutic groups.

Keywords: geriatric patient, ginkgo, grapefruit, herbal preparations, interactions, licorice, St. John's wort.

Published: March 14, 2022  Show citation

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Sychrová A. Herbal preparations and their drug interactions in routine outpatient practice. Praktické lékárenství. 2022;18(1):E38-55.
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