Praktické lékárenství – 1/2019

www.praktickelekarenstvi.cz / Prakt. lékáren. 2019; 15(1e): e54–e59 / PRAKTICKÉ LÉKÁRENSTVÍ e59 FYTOTERAPIE KONJAC – OBSAHOVÉ LÁTKY A LÉČIVÉ ÚČINKY 3. Behera SS, Ray RC. Konjac glucomannan, a promising polysaccharide of Amorpho- phallus konjac K. Koch in health care. Int J Biol Macromol. 2016; 92: 942–956. 4. Kite GC, Hetterscheid WLA. Phylogenetic trends in the evolution of inflorescence odours in Amorphophallus. Phytochemistry. 2017; 142: 126–142. 5. Tester RF, Al-Ghazzewi FH. Beneficial health characteristics of native and hydrolysed kon- jac (Amorphophallus konjac) glucomannan. J Sci Food Agric. 2016; 96(10): 3283–3291. 6. Chen X, Yuan LQ, Li LJ, Lv Y, Chen PF, Pan L. Suppression of gastric cancer by extract from the tuber of Amorphophallus konjac via induction of apoptosis and autophagy. On- col Rep. 2017; 38(2): 1051–1058. 7. Chen HL, Sheu WH, Tai TS, Liaw YP, Chen YC. Konjac supplement alleviated hypercho- lesterolemia and hyperglycemia in type 2 diabetic subjects – a randomized double-blind trial. J Am Coll Nutr. 2003; 22(1): 36–42. 8. Sawai S, Mokhtar MS, Safwani WKZW, Ramasamy TS. Suppression of the viability and proliferation of HepG2 hepatocellular carcinoma cell line by konjac glucomannan. Antica- ncer Agents Med Chem. 2018. doi: 10.2174/1871520618666180307143229. 9. Onishi N, Kawamoto S, Nishimura M, Nakano T, Aki T, Shigeta S, Shimizu H, Hashimoto K, Ono K. A new immunomodulatory function of low-viscous konjac glucomannan with a small particle size: its oral intake suppresses spontaneously occurring dermatitis in NC/ Nga mice. Int Arch Allergy Immunol. 2005; 136(3): 258–265. 10. Walsh DE, Yaghoubian V, Behforooz A. Effect of glucomannan on obese patients: a cli- nical study. Int J Obes. 1984; 8(4): 289–293. 11. Keithley J, Swanson B. Glucomannan and obesity: a critical review. Altern Ther Health Med. 2005; 11(6): 30–34. 12. Zhang MY, Huang CY, Wang X, Hong JR, Peng SS. The effect of foods containing refi- ned Konjac meal on human lipid metabolism. Biomed Environ Sci. 1990; 3(1): 99–105. 13. Arvill A, Bodin L. Effect of short-term ingestion of konjac glucomannan on serum cho- lesterol in healthy men. Am J Clin Nutr. 1995; 61(3): 585–589. 14. Vuksan V, Jenkins DJ, Spadafora P, Sievenpiper JL, Owen R, Vidgen E, Brighenti F, Josse R, Leiter LA, Bruce-Thompson C. Konjac-mannan (glucomannan) improves glycemia and other associated risk factors for coronary heart disease in type 2 diabetes. A randomized controlled metabolic trial. Diabetes Care. 1999; 22(6): 913–919. 15. Vuksan V, Sievenpiper JL, Owen R, Swilley JA, Spadafora P, Jenkins DJ, Vidgen E, Bri- ghenti F, Josse RG, Leiter LA, Xu Z, Novokmet R. Beneficial effects of viscous dietary fiber from Konjac-mannan in subjects with the insulin resistance syndrome: results of a control- led metabolic trial. Diabetes Care. 2000; 23(1): 9–14. 16. Chen HL, Cheng HC, Wu WT, Liu YJ, Liu SY. Supplementation of konjac glucomannan into a low-fiber Chinese diet promoted bowel movement and improved colonic ecolo- gy in constipated adults: a placebo-controlled, diet-controlled trial. J Am Coll Nutr. 2008; 27(1): 102–108. 17. Loening-Baucke V, Miele E, Staiano A. Fiber (glucomannan) is beneficial in the treatment of childhood constipation. Pediatrics. 2004; 113(3): e259–264. 18. Salas-Salvadó J, Farrés X, Luque X, Narejos S, Borrell M, Basora J, Anguera A, Torres F, Bulló M, Balanza R; Fiber in obesity-study group. Effect of two doses of a mixture of soluble fib- res on body weight and metabolic variables in overweight or obese patients: a randomi- sed trial. Br J Nutr. 2008; 99(6): 1380–1387. 19. Sood N, Baker WL, Coleman CI. Effect of glucomannan on plasma lipid and glucose concentrations, body weight, and blood pressure: systematic review and meta-analysis. Am J Clin Nutr. 2008; 88(4): 1167–1175. 20. Onakpoya I, Posadzki P, Ernst E. The efficacy of glucomannan supplementation in overweight and obesity: a systematic review and meta-analysis of randomized clinical trials. J Am Coll Nutr. 2014; 33(1): 70–78. 21. EFSA (European Food Safety Authority). Re-evaluation of konjac gum (E 425 i) and kon- jac glucomannan (E 425 ii) as food additives. EFSA Journal. 2017; 15(6): 4864.