609
www.praktickelekarenstvi.cz550715901901162343533734615075796446977287978629369681044111011831228130213851441149115661598162416941761
e2797617148020186175264
AKTUÁLNÍ71882940227122239349476597693822881
FARMAKOTERAPIE81062940227100218330490615733863967106811841312142214781582
Neuroprotektivní7946508018869124194255325386446516568623685743773839910939
účinky8911508018871130159230291358
statinů9296508018856112174221251322392
PRAKTICKÉ80737159019080160258338422459552632710
LÉKÁRENSTVÍ88197159019074149229330411488590663741833870
24.550874015767128154
McFarland7328760155106164221273309336392460530
AJ,1290876015581129148
Davey1467876015589146201262318
AK,1813876015581144168
McDermott20108760155106163245308344450518556599
CM,2637876015579179201
Grant2867876015585123181249286
GD,3181876015586169186
Lewohl3395876015563124216283352378
J,380187601555069
Anoopkumar-Dukie38998760155801482172863574114795836406777107958639169441006
S.493387601556587
Differences5501036015584110144179240277337405462521568
in1147103601552997
statin1272103601555292150187213280
associated15811036015561108154222280306362399459530
neuroprotection21391036015573135202238304375412479516576634676701769838
corresponds30051036015561126164201261308378447516585631
with36651036015596122161229
either3923103601556691130198260296
decreased42481036015573135193230290346392455525
production480210360155741121785501196015571138194237262330398
of977119601556699
IL-1β1105119601552581105159220
or13531196015567104
TNF-α14851196015558141200236307
in1821119601552492
an19411196015557124
in2094119601552492
vitro2214119601555683122158225
model246711960155104172243305331
of2827119601556699
neuroinflammation-induced2955119601556712919623229932439242145351061471977681383990697510141041110811781245130213611432
neurodegeneration.441511960155671301972332993704325035655501356015570132168227264290357426448
Toxicol10261356015561120174199256321348
Appl14031356015576146216243
Pharmacol16751356015565131188225330388445510537
2018;22401356015564124180234254
344:25221356015563126193212
56–73.27631356015563124192247308328
25.5501514015766130153
Mora7311516015595163199256
S,1015151601555575
Glynn11181516015575101156224291
RJ,14361516015560107125
Boekholdt15891516015560128190242311378404472510
SM,21271516015555151173
Nordestgaard23271516015578145181248308354394460516571607673
BG,30281516015560139160
Kastelein32161516015559118163202261286347371438
JJ,368115160155408099
Ridker3808151601556085153205264300
PM.41361516015559154177
On-treatment43411516015581149187225261320375412515576643679
non-high-density5501676015569137206245314339408475514586648715761785824884
lipoprotein1462167601552348117186257294360397456481549
cholesterol,20391676015553121189215277323363423459525552571
apolipoprotein26391676015554124193219244313382453490556593653678745
B,3412167601556182
triglycerides,352216760155357298167192248303363399425494556602624
and41741676015554122191
lipid4393167601552348117143212
ratios4634167601553392129154222268
in4930167601552390
relation550183601553899125182219245312381
to9591836015542107
residual1095183601553999146171240307364390
vascular15131836015560118165222289315371408
risk1949183601554066111164
after2141183601556193137197233
treatment2402183601554279139195233338400468505
with29351836015595121160228
potent31921836015573142180239307344
statin3565183601554989148185210278
therapy:38711836015542110172208267337392414
JUPITER43141836015546125189213273334397
(justification4739183601553665131177217243550199601553163120178215241308377
for9551996015535102139
the11231996015540108170
use13221996015569115177
of15281996015569102
statins1659199601554989147184210277323
in2011199601552795
prevention:21341996015572109170227287355392418485554573
an27361996015559127
intervention2891199601552895132192229291351419456482549618
trial3537199601554178104160186
evaluating37511996015564121179205272329366392459529
rosuvastatin)43081996015539105152218276334380421479516541609638
J49741996015546
Am5502156015576181
Coll7592156015574140167192
Cardiol9792156015574133169237262330356
2012;13642156015563124179231251
59:16442156015563120141
1521–1528.18142156015563115174229287340392451511533
26.5502314015767130156
Newman7342316015586148240346403471
CB,12332316015577140161
Preiss14222316015568103163189234280
D,17312316015586103
Tobert18632316015563122193256293336
JA,22282316015547118142
Jacobson23982316015547104161227297344412481
TA,29072316015563128152
Page30872316015568124194256
RL33712316015568126
2nd,3525231601556635872323090418336712316015523
Goldstein37222316015584153180249295335395420487
LB,42382316015560124145
Chin44122316015576143169236
C,4676231601557798
Tannock480323160155631111795502476015569137195247
LR,8262476015553117140
Miller9942476015596122147172233269
M,12912476015597119
Raghuveer14382476015561119188255321379439502538
G,2004247601557698
Duell21312476015579147209234259
PB,24182476015561123143
Brinton2589247601556198124191227292361
EA,29782476015556132155
Pollak31612476015561126152177233286
A,3475247601557295
Braun3598247601556198156222289
LT,39162476015553103116
Welty406024760155102160186224284
FK;43722476015556116141
American45412476015571175237273299355413480
Heart5502636015582144200237280
Association8582636015584133180248306331387425450518586
Clinical14732636015582107132199224281339364
Lipidology,1866263601556692161187257325351419490547561
Lipoprotein,2456263601556692161231301339405442502527595615
Metabolism310026360155108171209267337407433458504608
and37362636015567135204
Thrombosis39692636015568138174240346416485532556602
Committee,45992636015582148253358383550279601554083142205225
a8032796015564
Joint8952796015545113139207243
Committee11672796015579144250354379418461521584
of17792796015574107
the19142796015545113175
Council21182796015579144212280337362387
on25342796015573142
Atherosclerosis,27052796015580117185247283349396453479540577643690714760781
Thrombosis35152796015565135171238343413482529554599
and41422796015564132201
Vascular43722796015571126172229296322379415
Biology4816279601557095163550295601552895166223
and8012956015560128198
Council10272956015575141209277334359384
on14402956015570138
Lifestyle1607295601555985118179226266326353415
and20502956015560128198
Cardiometabolic22762956015576134170238263331436498537595665734761786842
Health;31472956015583145201227265333352
Council35282956015575141209276333358384
on39402956015570139
Cardiovascular41072956015576134170238263331387446492549616642699735
Disease487029560155861125503116015548111167213275
in854311601553199
the9813116015544112175
Young;11843116015570129197265334354
Council15663116015579144212280337362387
on19823116015573141
Clinical21523116015578103128196221277335361
Cardiology;25423116015578136172240265333360428498555577
and31473116015564131201
Stroke33763116015565101138204258319
Council.37233116015578144212280336362387408
Statin41593116015565101159196222289
Safety44773116015564123155216255315
and48203116015563131201
Associated5503276015576125172240298323379417476547
Adverse11253276015579147205266302350412
Events:15663276015563119179247284333353
A19483276015578
Scientific20553276015560117142204272309334364396452
Statement2536327601556399157194254358421489526
From3090327601556396162268
the33863276015543111173
American35873276015579184246282309365423491
Heart41063276015585147203240283
Association.44173276015579128174242300326382419445513581603
Arterioscler5503436015576113156216252278346393450475537574
Thromb11523436015560131167233338408
Vasc15893436015566121167224
Biol1842343601556591159185
2019;20563436015563124179232253
39(2):23373436015564122155215245264
e38-e81.26303436015563124185224289352407421
27.5503594015766127139
Ntolkeras7173596015578116181207258318354411457
G,1202359601557698
Barba13273596015561118154224282
C,1636359601556990
Mavropoulos17543596015596152207244309379448515540607653
A,2434359601557194
Vasileiadis25563596015561115161185210271295351420444489
GK,30733596015576138162
Dardiotis32633596015579135171237262329366391435
E,3726359601555677
Sakkas38313596015555112165219278324
LI,418235960155547999
Hadjigeorgiou43093596015576133202227251319380449485552577644711
G,5503756015581103
Bogdanos6823756015563132202272329397465512
DP.12223756015582146151
On14023756015584153
the15843756015537105168
immunoregulatory17803756015525129233300368436473534604671697754791857894955
role27633756015536102129191
of29823756015567100
statins3110375601554686144182207275320
in3459375601552492
multiple357937560155104171197235261330357419
sclerosis:40273756015545102128190226292339364409429
the44853756015537105168
effects4681375601556194129190248290339
on5503916015569138
Th177163916015561131182233
cells.9783916015558117143168214236
Immunol12433916015527131236303371439466
Res17373916015566128175
2019;19403916015564124180232253
67(4–5):22223916015563121148206273333364383
310–324.26333916015564118173241298355411431
28.5504074015767131158
Quintana-Pájaro7364076015583152177244281339407464503569625651707744810
LJ,15744076015554102122
Ramos-Villegas17244076015561119224292339375439466492517579649706753
Y,2505407601556173
Cortecero-Sabalza26064076015570136173216276334394430496537592650720779804855915
E,3549407601555778
Joaquim36564076015540109167236303329433
AF,41174076015572130137
Agrawal42834076015571140176234326384409
A,4721407601557295
Narvaez-Rojas484540760155781365504236015538100159221273310376445471527573
AR,11524236015574138161
Moscote-Salazar13414236015599168215272337375434475530588614671723782819
LR.21884236015556120145
The23614236015559129191
Effect2580423601555991127187245288
of28964236015567100
Statins3025423601555894152189215282328
in3382423601552592
Epilepsy:35034236015558127153179241311357415437
A39694236015574
Systematic40714236015560112160200260364421459484541
Review.46404236015564126183209271363380
J5504396015545
Neurosci6234396015583146213249315362419444
Rural10964396015565132169227253
Pract13774396015566101159216259
2018;16644396015564124180234253
9(4):1946439601556396154183202
478–486.21774396015563119178245310375438459
29.5504554015767131153
Ridker731455601557096165218278315
PM,10744556015569166188
Danielson12914556015587144212237299325370438507
E,1826455601556586
Fonseca19414556015563130198244306364422
FA,23924556015564131154
Genest25754556015584148215278325365
J,2968455601554968
Gotto30654556015584154191234299
AM33934556015580180
Jr,360245560155488599
Kastelein37304556015568128174215274301362388455
JJ,4213455601554990110
Koenig43514556015569135199266291361
W,474045560155110125
Libby48944556015561875504716015572142198
P,776471601556771
Lorenzatti8754716015560126164224292343403440483508
AJ,14124716015577125144
MacFadyen158547160155103160217275326396452513581
JG,21944716015547127149
Nordestgaard23714716015585153190258320367407475532589625693
BG,30924716015567147169
Shepherd32904716015562129191261330392429496
J,3815471601554665
Willerson390947160155108135160185247284332400468
JT,44064716015546107120
Glynn45554716015582109165235302
RJ;48864716015567114134
JUPITER5504876015545125188212272333396
Study9744876015567103171240297
Group.12994876015587125191259329349
Rosuvastatin16764876015572140187253311369416456514551577644
to23494876015546112
prevent24894876015578115175232293361398
vascular29154876015565124170227294320377413
events33564876015570127187255292341
in37254876015533101
men385448760155113175243
and41264876015565132202
women435648760155100168273335403
with478748760155100127165233
elevated550503601556389151208266304363434
C-reactive1013503601557495133193249306348374431492
protein.15345036015571109175212272297365386
N19495036015583
Engl20605036015561128198223
J23125036015544
Med238550360155101163234
2008;26485036015563123188251271
359(21):29475036015564122178211271326349368
2195–207.33445036015563118171231296351411469476
30.5220874015767131157
Schultz5405876015559116184251276315369
JL,5803876015543100122
Nopoulos5954876015581149220289357383451497
PC,6480876015563136157
Killoran666687601556391116141209246305372
A,706787601557498
Kamholz7193876015563123227295363390441
JA.7663876015543114139
Statin783087601555995153190216283
use8142876015567113175
and8345876015558125195
delayed8568876015569131157214269329400
onset8997876015567135181244282
of9308876015567100
Huntington's94368760155811482155220103601554066133203242308376394439
disease.5687103601557196142204260306368388
Mov610410360155101169226
Disord63581036015584110156224261329
2019;67151036015564124180232253
34(2):69971036015563126160220250269
281–285.72941036015564123179237292352412431
31.52201194015766124144
Tapia-Perez53911196015556104174199256294360418455515566
JH,59861196015540120141
Rupa61551196015561128197255
R,6438119601556285
Zilke6551119601556590115168228
R,6807119601556184
Gehring69191196015577140207243269336405
S,7353119601555576
Voellger74571196015562125188214239308369406
B,7891119601556181
Schneider80011196015555112179247308333402464500
T.8529119601555670
Continued86271196015570135203240265332399460530
statin9186119601554483141178204271
therapy948511960155351031655220135601553896166221
could54691356015553118186211280
improve57771356015523127196233299355415
the62211356015535103165
outcome64141356015565132171224290394456
after6899135601555486130189225
spontaneous71531356015544113182250286344412473542610655
intracerebral7836135601552390127163222278337374434503540598624
hemorrhage.84881356015565127231299336373441498568629648
Neurosurg91651356015578140207243309355421457524
Rev52201516015566128185
2013;54331516015564124180232250
36:57111516015564125145
279–287.58841516015564122181248303363421428
32.52201674015766125148
Tapia5394167601555398165188241
Perez56611676015558113147204253
JH,59391676015538115133
Yildiz6098167601555782104170192240
OC,63641676015579150168
Schneider65581676015553107171236294317383441475
T,7058167601555363
Nimsky7147167601557598198241291348
C.7520167601556786
Meta-analysis76311676015594153188243279333398451474527571593635
of8292167601556191
statin8409167601554178133167190254
use86881676015562105164
for8877167601552791125
the9027167601553398157
acute92091676015552106170206262
therapy94971676015532971565220183601553894161214
of5460183601556697
spontaneous55831836015546112179245279335400460526591635
intracerebral6244183601552489123158213268325359416484518574597
hemorrhage.68671836015567127229294329364430485552611628
J75211836015542
Stroke7589183601555891126189241298
Cerebrovasc79131836015572129163221288323386440496539594
Dis85331836015581105148
2015;87061836015561119172222236
24:89681836015561114131
2521–2526.91251836015560120176228283336395451508527
33.52201994015767129154
Tobert54021996015567127197261297340
JA.57711996015551122147
Lovastatin59461996015565131187246292332390428453521
and64951996015565133203
beyond:67261996015578141197264332402422
the71761996015547115177
history73811996015576101147187252290350
of77601996015575108
the78971996015546114176
HMG-CoA81011996015588188267308385451524
reductase86531996015545105176243300342400446508
inhibitors.91901996015533100168193263289328393431478501
Nat52202156015583140178
Rev54262156015566128185
Drug56392156015585122190260
Discov59272156015585111156213279335
2003;62902156015564124189247265
2(7):6584215601556392154187206
517–526.68192156015563117168225285343403425
34.52202314015767133158
Vergouwen54062316015572130167234302370463524592
MD,602623160155107189207
de62612316015576138
Haan64282316015587145202269
RJ,67262316015571119138
Vermeulen68932316015571129166271334401426488556
M,747723160155107130
Roos76352316015571140209256
YB.79192316015571136158
Statin81062316015566102160197223290
treatment8425231601554582143199236341404471508
and89622316015565132202
the91922316015546114177
occurrence939723160155751331872545220247601553876136204261320
of55692476015570103
hemorrhagic57012476015571133238306343381449507576601658
stroke6387247601555090127194248308
in6723247601552996
patients68482476015573131169194256324361409
with72862476015595121160228
a75422476015561
history7631247601557095140181246283344
of80042476015570103
cerebrovascular81352476015560119156216286323389446504550608675700757793
disease.8957247601557297143205261307370389
Stroke9375247601556197134200254315
2008;52202636015563124188251271
39:55202636015563122143
497–502.56922636015563121179236296357415435
35.52202794015767129153
Vráblík54012796015567101160230256281337
M.576727960155101124
Farmakoterapie59192796015560112148254311364431468528565623693719780
dyslipidemie67282796015571127174200225294320390451556581643
2.7399279601556484
vydání,75122796015558119188245312337358
Maxdorf789827960155101159215283351388425
Praha83522796015565100159227284
2016.86642796015564124180234256
36.52202954015767131158
Wilson540629560155107134160205273342
PWF,57762956015566171230237
Polonsky60422956015565130157225293339392452
TS,65232956015560120141
Miedema669229560155102127189260322426483
MD,720429560155101184201
Khera74332956015565136198234293
A,77542956015576100
Kosinski78822956015565132179203271317369397
AS,83072956015577137158
Kuvin84932956015565131189215283
JT.88042956015545106120
Systematic89532956015560112160200260364421459484541
Review952229560155661285220311601555985147239
for5487311601553097134
the56503116015535103165
201858443116015559119175229
AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA610231160155711512252743394094765245906677378058719339811047112511881254130213681432150515521618168717501847189319592041211221612226230323612405247125342600267427232789284929112984303131143170324832973362343435153588
Guideline52203276015581149174244306332356424486
on57343276015565134
the58973276015536104166
Management60913276015597155222279349411516578646683
of6802327601556598
Blood6929327601556188155225295
Cholesterol:72533276015570137205232294341381441477543570590
A78713276015572
Report79723276015565128198267304347
of8348327601556598
the84743276015536104167
American86693276015572177239276302358416484
College91823276015570135162187249319381
of9592327601556598
Cardiology/American5220343601557413216923626232935642449555159265776282486188794410021070
Heart63183436015579141197234277
Association66233436015573122169237295320376414439507576
Task72273436015557106152205
Force74603436015557123161215275
on77633436015566135
Clinical7926343601557197121189214270328354
Practice8309343601556297156213255280337396
Guidelines.87343436015578146171240302328353420483530552
Circulation93153436015570961321872542803365220359601554066133202
2019;54503596015564124180232253
139(25):57323596015563115174206266328360379
e1144–e1161.61393596015563115162216282349414466513567620634
37.52203754015767127140
Wlodarczyk538837560155102130197268325361415470530584
J,6001375601554059
Sullivan60893756015555122147172197254312380
D,6497375601558097
Smith66223756015556159184223291
M.69413756015597120
Comparison70893756015570135240310368405431476544612
of7730375601556497
benefits78553756015568131199260290322360409
and82923756015555122191
risks8512375601553460105157208
of8749375601556497
rosuvastatin88743756015534100147213271329375415473510536603
versus9505375601555411515152203916015548115160
atorvastatin5409391601555997162199261320366406464502527595
from6032391601553473139244
a63053916015559
meta-analysis639339160155106168207265304361429486511567615639685
of71063916015570103
head-to-head72373916015570132188258297335401442511574630700
randomized7965391601553997165234302408433484544615
controlled86093916015558123192229266332359384445516
trials.9154391601554077103160185230253
Am94353916015577182
J96453916015545
Cardiol52204076015574132169236262329356
2008;56054076015563123188251271
102(12):59044076015563118176205261313343362
1654–1662.62954076015563117177240306360415478537557
38.52204234015767134164
Yan54144236015572126197
J,5642423601555173
Qiao57464236015594123182253
L,6030423601556490
Tian6151423601556798157227
J,6409423601555274
Liu6514423601556493162
A,67074236015583109
Wu684742360155113181
J,7059423601555173
Huang71634236015589159218289361
J,7555423601555173
Shen76594236015567137202272
M,796242360155108133
Lai81264236015565127154
X.83114236015578104
Effect84464236015567101142205266311
of87884236015575111
statins8930423601555598159199227297345
on93064236015576147
Parkinson's948442360155721311705220439601555586156205276348369417
disease:56684396015574102150215275324389412
A61124396015588
systematic62314396015552113163206269377437477505565
review68274396015551114174204268363
and72224396015571142215
meta-analysis.746843960155119185226287329389460520548607658685734759
Medicine825843960155114179253281341369439504
(Baltimore)87944396015547113175203245273381452492556588
2019;94134396015576139198253277
98(12):52204556015563128163221276309330
e14852.55814556015566120177244307368391
39.52204714015767129151
Yang53994716015562114181251
D,5678471601558198
Knight58054716015561131156225293330
RA,61634716015563140163
Han63554716015578135203
Y,6587471601556173
Karki66894716015561121157211239
K,6956471601556186
Jianfeng7071471601554166122190222283351421
Z,7520471601556788
Ding76374716015580107174244
C,7909471601557192
Chopp80294716015571138207277348
M,84054716015598120
Seyfried85544716015557119174212251277338409
D.8991471601558199
Vascular91184716015563118164221288314371407
recovery955447160155349552204876015558123179239275336
promoted55844876015567104170274342380439509
by61214876015567122
atorvastatin6271487601555592157194256313359399457494519586
and68864876015554121190
simvastatin7105487601554368171226284330370428465490557
after7690487601555587130190226
experimental79444876015559114184247283309413474542579636662
intracerebral8634487601552289126163221277336373432502539597622
hemorrhage:9285487601556512623029833537252205036015569125194255275
magnetic552350360155101157226293354392417473
resonance6024503601553393139206274330397453512
imagingand65645036015522125181250275341410466533602
histological7194503601556489134173238264331401426481539564
study.7786503601554383149218274289
J81035036015540
Neurosurg81705036015578140206242307353418454521
2011;87195036015558118172219230
114:89775036015558105159178
1135–1142.91825036015559105156214278331377431487507