Prakt. lékáren. 2011; 7(1): 30-33

New medicinal substances in extemporaneous prescription, part 7 - alpha-tocopherol acetate

PharmDr.Zbyněk Sklenář, Ph.D.1,2, Mgr.Kateřina Horáčková2
1 Vyšší odborná škola zdravotnická, Plzeň
2 Lékárna Na Rohožníku, Praha

Alpha-tocopherol acetate has been used as medicinal substance (vitamin E) for peroral, parenteral and topical preparationes. The aim

of the article is not to present the sometimes questionable therapeutic use of tocopherols but to provide basic information on the properties

and use of this substance and to present suitable examples of formulas because tocopherol is still used in some prescriptions of

extemporaneous preparations. The formulation can be easier now because alpha-tocopherol acetate has been available as a substance

for extemporaneous preparation in pharmacies since October 2010.

Keywords: tocopherols, alpha-tocopherol acetáte, magistral preparation, dithranol, Nasopanthil

Published: February 1, 2011  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Sklenář Z, Horáčková K. New medicinal substances in extemporaneous prescription, part 7 - alpha-tocopherol acetate. Pharmacy for Practice. 2011;7(1):30-33.
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Open full article

    References

    1. Rowe RC, Sheskey PJ, Owen SC. Pharmaceutical excipients 2004 (Singleuser version). [CD-ROM]. Washington, DC: Pharmaceutical Press and American Pharmacists Association, 2004.
    2. Melichar B, et al. Chemická léčiva. 3., přeprac. a dopl. vydání. Praha: Avicenum, 1987: 520-522 s.
    3. Murray RK, Granner DK, Mayes PA, Rodwell VW. Harperova Biochemie. 23. vyd., 3. české. Jinočany: Nakladatelství H&H 2001: 622-627 s.
    4. Saral Y, Uyar B, Ayar A, Naziroglu M. Protective Effects of Topical Alpha-Tocopherol Acetate on UVB Irradiation in Guinea Pigs: Importance of Free Radicals. Physiol Res 2002; 51(3): 285-290.
    5. Thiele JJ, Ekanayake-Mudiyanselage S. Vitamin E in human skin: organ-specific physiology and considerations for its use in dermatology. Mol Aspects Med. 2007; 28(5-6): 646-667. Go to original source... Go to PubMed...
    6. Pinnell SR. Cutaneous photodamage, oxidative stress, and topical antioxidant protection. J Am Acad Dermatol 2003; 48(1): 1-19. Go to original source... Go to PubMed...
    7. Kolektiv autorů. Remedia Compendium. 4., přeprac. a rozšíř. vyd. Praha: Panax Co, s. r. o, 2009: 946 s.
    8. Mikro-verze AISLP - Automatizovaný informační systém léčivých přípravků. [CD-ROM]. Ver. ČR 2010.2 pro MS Windows platná k 1. 4. 2010. Praha, 2010.
    9. Český lékopis 2009. 1. vyd. Praha: Grada Publishing, a.s., 2010: 3968 s.
    10. Di Mambro VM, Azzolini AE, Valim YM, Fonseca MJ. Comparison of antioxidant activities of tocopherols alone and in pharmaceutical formulations. Int J Pharm. 2003; 27; 262(1-2): 93-99. Go to original source... Go to PubMed...
    11. Wynn RL, Meiller TF, Crossley HL. Drug information handbook for dentistry. 15th ed. Ohio: Lexi-Comp, 2009: 2223 p.
    12. Sklenář Z. Magistraliter receptura v dermatologii. 1. vyd. Praha: Galén, 2009: 441 s.
    13. Garbe C, Reiman H. Dermatologische Rezepturen. 2. vyd. Gregor Thieme Verlag, 2005: 97 s. Go to original source...
    14. Duchková H. Kyselina boritá a boritany - riziko ich používania. Prakt Lék 1990; 70(14): 552-554.
    15. Sklenář Z. Úskalí individuální přípravy léčivých přípravků v lékárnách - vybrané příklady I. Prakt Lékáren 2008; 4(5): 247-250.

    Return to the content


    Pharmacy for Practice

    Madam, Sir,
    please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
    Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

    I declare:

    1. that I have met the above instruction
    2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited

    No
    Yes

    If your statement is not true, please be aware
    that brings the risk of danger to their health or the health of others.