Prakt. lékáren. 2014; 10(5): 185-189

Basiscreme DAC - a novel cream basis for extemporaneous preparation, part 1

Jan Hašek

Lékárna U Matky Boží, Doksy

Basiscreme DAC (Cremor basalis DAC) is a newly available cream basis with the character of a hydrophilic cream (an oil-in-water emulsion)

that serves as a vehicle for extemporaneous preparation of semisolid topical products. It is of ambiphilic nature and thus can accommodate

both hydrophilic and lipophilic substances without disturbing the emulsion system. This cream basis is used in foreign formulations and,

to a certain degree, can be referred to as a universal non-ionic vehicle allowing to incorporate a whole range of medicines, including some

problematic substances and their combinations. Due to its comprehensiveness, the article is divided into two parts, the first of which deals

with the galenic characteristics of the Basiscreme DAC cream basis as well as the options for use in extemporaneous preparation through

examples of standardized formulations.

Keywords: extemporaneous preparation, ambiphilic creams, dermatological formulation, topical corticosteroids, DAC/NRF

Published: October 24, 2014  Show citation