Prakt. Lékáren. 2016; 12(1e) [Med. praxi. 2015;12(3):106-108]

Medical treatment for chronic heart failure

Gabriela Štěrbáková
Kardiologické oddělení FN a LF UK Plzeň

Heart failure is a frequent disease with a serious morbidity and mortality. The article summarizes new recommendations for pharmacologicaltherapy for chronic heart failure. The mainstay of treatment is to interfere with neurohumoral activation that plays a crucial role in thepathophysiology of heart failure, in particular with beta blockers and ACE inhibitors; in the case of persistent symptomatology with mineralocorticoidreceptor blockers. The results of studies of the angiotensin receptor neprilysin inhibitor appear promising. The recommendationsnewly include ivabradine.

Keywords: chronic heart failure, pharmacotherapy, neurohumoral activation interference, ivabradine

Published: March 1, 2016  Show citation

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Štěrbáková G. Medical treatment for chronic heart failure. Praktické lékárenství. 2016;12(E-verze 1/16):.
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    References

    1. Špinar J, Vítovec J, Hradec J, Málek I, Meluzín J, Špinarová L, Hošková L, Hegarová M, Ludka O, Táborský M. Czech Society of Cardiology guidelines for the diagnosis and treatment of chronic heart failure 2011. Cor et Vasa 2012; 54: e114-e1341. Go to original source...
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