Prakt. lékáren. 2017; 13(2): 60-62 | DOI: 10.36290/lek.2017.006

Drug-induced photosensitivity

Hana Bakhouche, Martin Šíma, Ondřej Slanař
Oddělení klinické farmakologie a farmacie, Farmakologický ústav, 1. lékařská fakulta Univerzity Karlovy a Všeobecná fakultní nemocnice v Praze

Data suggest that more than 300 drugs are reported to be photosensitizers. However, the effect of only a few drugs have been

well described. It seems that many photosensitive reactions are underdiagnosed due to the difficulty to prove the relationship

between the drug and sun exposure. It is important to clarify this relationship to timely treat patients or better to take adequate

measures to prevent adverse effects.

Keywords: photosensitizing agents, phototoxicity, photoallergy, photosensitive contact dermatitis

Published: June 1, 2017  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Bakhouche H, Šíma M, Slanař O. Drug-induced photosensitivity. Praktické lékárenství. 2017;13(2):60-62. doi: 10.36290/lek.2017.006.
Download citation

References

  1. Moore DE. Drug-induced cutaneous photosensitivity: incidence, mechanism, prevention and management. Drug Saf. 2002; 25(5): 345-372. Go to original source... Go to PubMed...
  2. Zuba EB, Koronowska S, Osmola-Mańkowska A, Jenerowicz D. Drug-induced Photosensitivity. Acta Dermatovenerol Croat. 2016; 24(1): 55-64. Go to PubMed...
  3. Onoue S, Seto Y, Sato H, Nishida H, Hirota M, Ashikaga T, Api AM, Basketter D, Tokura Y. Chemical photoallergy: photobiochemical mechanisms, classification, and risk assessments. J Dermatol Sci. 2017; 85(1): 4-11. Go to original source... Go to PubMed...
  4. European Medicines Agency. ICH guideline S10. Guidance on photosafety evaluation of pharmaceuticals.EMA/CHMP/ICH/752211/2012. Dostupný z: http://www.ema.europa.eu/docs/en_GB/document_library/Regulatory_and_procedural_guideline/2012/12/WC500136404.pdf.
  5. Cazzaniga S, Naldi L, Lecchi S, Kürzinger ML, Auclert L, Gori M, Chosidow O,Hercogova J. A pilot study on the incidence of severe photosensitivity reactions leading to hospitalization linked to topical ketoprofen and other medications in selected European regions. Pharmacol Res Perspect. 2016: 4(3): e00225. Go to original source... Go to PubMed...
  6. Monteiro A F, Rato M, Martins C. Drug-induced photosensitivity: Photoallergic and phototoxic reactions. Clin Dermatol. 2016: 34(5): 571-581. Go to original source... Go to PubMed...
  7. Wlodek C, Narayan S. A reminder about photo-onycholysis induced by tetracycline, and the first report of a case induced by lymecycline. Clin Exp Dermatol. 2014: 39(6): 746-747. Go to original source... Go to PubMed...
  8. de Guidi G, Bracchitta G, Catalfo A. Photosensitization reactions of fluoroquinolones and their biological consequences. Photochem Photobiol. 2011; 87(6): 1214-1229. Go to original source... Go to PubMed...
  9. Barbosa NS, Wetter DA. Bullous phototoxicity from voriconazole. J Emerg Med. 2014; 46(3): e83-84. Go to original source... Go to PubMed...
  10. Sommer M, Trautmann A, Stoevesandt J. Relief of photoallergy: atorvastatin replacing simvastatin. J Investig Allergol Clin Immunol. 2015; 25(2): 138-140.
  11. Gómez-Bernal S, Alvarez-Pérez A, Rodríguez-Pazos L, Gutiérrez-González E. Rodríguez-Granados, M. T. and Toribio, J. Photosensitivity due to thiazides. Actas Dermosifiliogr. 2014; 105(4): 359-366. Go to original source... Go to PubMed...
  12. Bakkour W, Haylett AK, Gibbs NK, Chalmers RJ, Rhodes LE. Photodistributed telangiectasia induced by calcium channel blockers: case report and review of the literature. Photodermatol Photoimmunol Photomed. 2013: 29(5): 272-275. Go to original source... Go to PubMed...
  13. Sánchez-Borges M, González-Aveledo LA, Photoallergic reactions to angiotensin converting enzyme inhibitors. J Eur Acad Dermatol Venereol. 2011; 25(5): 621-622. Go to original source... Go to PubMed...
  14. Isaacs T, Ngwanya MR, Dlamini S, Lehloenya RJ. Annular erythema and photosensitivity as manifestations of efavirenz-induced cutaneous reactions: a review of five consecutive cases. J Antimicrob Chemother. 2013; 68(12): 2871-2874. Go to original source... Go to PubMed...
  15. Jaworski K, Walecka I, Rudnicka L, Gnatowski M, Kosior D A. Cutaneous adverse reactions of amiodarone. Med Sci Monit. 2014; 20: 2369-2372. Go to original source... Go to PubMed...
  16. Harth Y, Rapoport M. Photosensitivity associated with antipsychotics, antidepressants and anxiolytics. Drug Saf. 1996; 14(4): 252-259. Go to original source... Go to PubMed...
  17. Goldstein J, Patel AB, Curry JL, Subbiah V, Piha-Paul S. Photoallergic reaction in a patient receiving vandetanib for metastatic follicular thyroid carcinoma: a case report. BMC Dermatol. 2015; 15: 2. Go to original source... Go to PubMed...
  18. Gozali MV, Zhou BR, Luo D. Update on treatment of photodermatosis. Dermatol Online J. 2016; 22(2). Go to original source...




Pharmacy for Practice

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.