Praktické lékárenství, 2010, issue 2

Editorial

Mixtura velikonoční (aneb Úvahy farmaceutického staříka nad péčí o zdraví a lécích)

prof. RNDr. PhMr. Dr. h. c. Jan Solich, CSc.

Prakt. lékáren. 2010; 6(2): 59

Current pharmacotherapy

Antiepileptics and their clinical use in epileptology

doc.MUDr.Robert Kuba, Ph.D.

Prakt. lékáren. 2010; 6(2): 62-66

Antiepileptics are drugs used to treat or suppress epileptic seizures. Currently, over twenty antiepileptic drugs are registered in the Czech Republic. Some of them are frequently used in all types of epileptic seizures while others are indicated in limited circumstances due to selection efficiency or poor tolerability. The widely used classic antiepileptics include carbamazepine and valproates and the widely used novel ones include lamotrigine, levetiracetam and topiramate.

Local drugs for oral mucosa diseases

PharmDr.Jan Gajdziok, Eliška Tajovská, PharmDr.Martina Bajerová, PharmDr.Zuzana Chalupová, Ph.D.

Prakt. lékáren. 2010; 6(2): 68-72

The article builds on previously published issue about diseases of the oral mucosa. It is focused on the possibility of specific pharmacotherapeutic intervention to mucosal diseases by local therapy with particular emphasis on local antiseptics, non-steroidal anti-inflammatory drugs, corticosteroids, topical antibiotics, chemotherapeutics, and antifungals.

Hearing loss and treatment options from the perspective of an otorhinolaryngologist

MUDr.Eva Mrázková, Ph.D., Mgr.Kristýna Richterová, Mgr.Petra Sachová

Prakt. lékáren. 2010; 6(2): 74-78

Hearing loss is one of the most common diseases in the population. The treatment of hearing loss depends on the site of origin of the disease in the auditory pathway, the causative factor and its duration and intensity. The prognosis of sudden hearing loss is the better, the sooner (within hours and days) intensive treatment is initiated. Individual treatment methods are mentioned. The results of all types of treatment for sudden sensorineural hearing loss are similar: 60–80 % of patients are cured, 20–30 % improve and 10 % to 25 % do not respond to treatment. In long-term hearing loss, medication therapy is not effective. Measures...

Onychomycosis

MUDr.Zuzana Kulíková

Prakt. lékáren. 2010; 6(2): 80-83

Onychomycosis is a mycotic infection of a nail apparatus that consists of a nailplate, nail matrix and a nailbed. The disease itself is not life threatening but could cause in patients and especially immunocompromised subjects serious complications. In some untreated forms it could cause significant pain that leads to psychological and social problems and decrease of patients’ quality of life.

Immunosuppression after kidney transplantation

prof.MUDr.Ondřej Viklický, CSc.

Prakt. lékáren. 2010; 6(2): 84-86

Successful kidney transplantation depends on the quality of the donor organ, surgical procedure and immunosuppressive regimen. Immediately before and shortly after transplantation, induction immunosuppression is used, based on T lymphocyte depletion or blockade of function. In patients at risk of rejection, antithymocyte globulin is used while, in patients at low risk, monoclonal antibody basiliximab against interleukin-2 receptor is used. Long-term immunosuppression mostly consists of a combination of calcineurin inhibitor (tacrolimus or cyclosporin A) together with mycophenolate mofetil, an inhibitor of purine synthesis, and steroids. When...

Clinical pharmacy

Immunosupressant dispensation and education of organ transplant recipients in chemist's

Mgr.Katarína Mikušová

Prakt. lékáren. 2010; 6(2): 87-90

Transplantation is considered as a „new chance for life“ for patients in end stage of a solid organ failure. However, it involves a lot of restrictions in patient common life. Health care of organ transplant recipients entails regular medical examinations, regime and diet recommendations and special rules in immunosupressive drug administration. These are necessary for solid organ graft acceptance and its right function. There are more drugs used to lower risk of transplant complications or to treat other patient comorbidities in organ transplant recipient medication. Patient with polypragmasy has to be explained rules how to take...

For pharmaceutical assistants

Atopic dermatitis and care of atopic skin

doc.MUDr.Olga Vohradníková, CSc.

Prakt. lékáren. 2010; 6(2): 92-96

Atopic dermatitis (AD) is one of the most common skin conditions affecting mainly children but also adults. The etiopathogenesis of the disease, its incidence and course and typical as well as less common clinical manifestations are briefly introduced. Complications of the course of AD are briefly mentioned. Major attention is paid to external treatment and preventive care of atopic skin, particularly in childhood. Risk and aggravating factors and options of systemic treatment are also mentioned.

Pharmacist and the Internet

Další vývoj ohledně německé e-karty

PharmDr.Martin Dočkal

Prakt. lékáren. 2010; 6(2): 101