Růže v lékárně

Mgr. Jan Pomykacz

Prakt. lékáren. 2013; 9(3): 107  

Geriatric patient and quality of life, geriatric pharmacotherapy

Iva Holmerová, Michaela Baumanová, Hana Vaňková, Petr Wija

Prakt. lékáren. 2013; 9(3): 114-117  

Demographic changes pose unprecedented challenges for the system of health and social care and ageing of the population will continue significantly in the following years. The elderly population is very heterogeneous. Geriatric patients, particularly fragile and dependent senior citizens, require a specific modification of health care, including acute, subsequent, and long-term care. The emphasis in care should be placed on evaluation of the functional status and support of self-sufficiency that is important for maintaining the quality of life in older age. STOPP/START criteria).

Compression therapy in practice

Sabina Sellner Švestková

Prakt. lékáren. 2013; 9(3): 117-119  

Compression therapy is very important conservative treatment method that is used to support the venous and lymphatic circulation, especially of the lower limbs, disorders of venous muscle pump function, in chronic venous insufficiency, varicose veins in the legs, failure and functional impairment of venous perforators, with venous ulcers and diseases of the lymphatic circulation of the lower limbs.

Fundamentals of prevention and treatment of kidney diseases

Romana Ryšavá

Prakt. lékáren. 2013; 9(3): 120-123  

Chronic kidney diseases affect nearly a tenth of our population and are becoming not only a medical issue, but also a social-economic problem. The best measures taken to prevent the development of advanced stages of disease include the implementation of screening programs to find patients with an existing renal injury or those at a high risk. Basic tests include measurement of serum creatinine and glomerular filtration rate, urine sediment analysis and proteinuria or microalbuminuria testing. Measures that can significantly slow down (or even stop) the progression of chronic nephropathies are treatment with angiotensin-converting enzyme inhibitors...

Retigabine (Trobalt®): a novel antiepileptic agent to treat pharmacoresistant focal epilepsy

Robert Kuba

Prakt. lékáren. 2013; 9(3): 110-112  

Retigabine is the most recent antiepileptic agent to have been introduced in the Czech market. It has a unique mechanism of action that involves inhibition of neuronal potassium channels. Based on the results of controlled clinical trials, its administration is indicated for the adjunctive treatment of adult patients with focal epilepsy with focal or secondarily generalized tonic-clonic seizures. The drug is administered by mouth three times a day in daily doses of 600 to 1 200 mg after previous titration. The most common adverse effects include dizziness, sleepiness, headache, and fatigue.

Drug-induced liver injury

Petr Červený

Prakt. lékáren. 2013; 9(3): 123-126  

The liver is the largest organ in the human body. It plays an essential role in the metabolism, synthesis, and storage of endogenous compounds as well as in detoxication and excretion of exogenous compounds. Hepatotoxicity refers to liver injury due to exposure to a chemical substance; iatrogenic injury is that which is induced by medicinal products. Medicinal products may have hepatotoxic effects not only as a result of overdose but, in many cases, even when used in therapeutic doses. The article deals with individual mechanisms of liver injury and particular drug groups.

Cannabis or THC, CBD, CB1, CB2 etc.

Jaroslav Peč

Prakt. lékáren. 2013; 9(3): 131-134  

Presented short review introduces basic information concerning phytocannabinoids and their relation to the human endocannabinoid system. Attention is focused on Sativex®, as the only one medicinal preparation containing cannabinoids registered in the Czech Republic. Based on Sativex® are listed perspectives of medicinal cannabis. Indications, adverse effects, contraindications and possible drug interactions are listed.

Optizorb® technology in acute pain managment

Boris Leštianský, Lenka Součková

Prakt. lékáren. 2013; 9(3): 127-130  

The new pharmaceutical drug technologies are designed to improve the pharmacokinetic properties of drug agents. In recent years, newer substances known as „superdisintegrants“ have been developed. These substances are more effective at low concetrations due to water absorption and faster disintegration of tablets. Newer commercially available non-opioid analgesics used in acute outpatient pain management are focused on fasting onset of effective analgesia and rapid control of pain.

Antioxidants and Degenerative Disease

Lubomír Opletal, Jakub Chlebek, Kateřina Macáková, Nina Benešová, Anna Hošťálková, Lucie Cahlíková

Prakt. lékáren. 2013; 9(3): 135-138  

Free radicals (more correctly called reactive oxygen and nitrogen species) along with environmental toxins are the most frequently cited sources of pathological effects on physiological processes in man and on the development of degenerative diseases (diseases of civilization). Numerous free radicals commonly occur in the organism because they are part of physiological processes (physical exercise, food processing, the body‘s immune defence). Their pathological effect is dependent on the number of these radicals and their type (biological half-time). Administration of antioxidants is problematic to a certain degree: an excessive intake...

vaginální kandidóza, intimní hygiena, probiotika, vaginální

Peter Koliba, Peter Koliba, jun.

Prakt. lékáren. 2013; 9(3): 139-141  

výplachy. Vaginal discomfort, intimate hygiene Review article on the issue of vaginal discomfort in women. This problem is one of the most common reasons for visiting the gynecologist. The cause of acute discomfort is bacterial vaginosis or vaginal candidiasis. The authors present a description of these diseases, and an overview of current therapeutic options. Addition to the important intimate hygiene procedures are also included products for intimate hygiene and probiotics and also products intended to vaginal irrigation, appropriate for prevention of vaginal discomfort. vaginal candidiasis, intimate hygiene, probiotics, vaginal...

Rhinosinusitis: role and possibilities of a pharmacist; place of nasal corticosteroids

Jiří Nevrlka

Prakt. lékáren. 2013; 9(3): 142-145  

Rhinosinusitis is undoubtedly among the most frequent diseases in childhood as well as adulthood. The recognition of rhinosinusitis per se is relatively easy even in the setting of routine pharmacy service. It is the determination of the etiopathogenetic nature of this condition that may be a challenge. For various reasons, therapeutic intervention is suitable even in the case of a seemingly mild course, particularly in chronic rhinosinusitis. The pharmacist can choose from a wide variety of preparations and drugs that can effectively affect the course of rhinosinusitis and bring relief from its symptoms. In addition to preparations acting...

18. kongres EAHP v Paříži (European Association of Hospital Pharmacists) 13.-15. 3. 2013

PharmDr. Marie Zajícová

Prakt. lékáren. 2013; 9(3): 130  

15. svazek Solutia - 2013 je již na webu

prof. RNDr. PhMr. Jan Solich, CSc.

Prakt. lékáren. 2013; 9(3): 134  

Pracovní den z historie farmacie a veterinární medicíny

Pavel Brauner

Prakt. lékáren. 2013; 9(3): 149  

Study on the relation of pharmacies and drugstores in Czechoslovak Republic (1918-1938)

Martina Lisá, Vilma Vranová2, Marcela Kallusová3

Prakt. lékáren. 2013; 9(3): 146-149  

Conflicts of competencies between pharmacists and druggists can be traced back to the very origins of both professions. They culminated in the early 20th century when the distribution of their powers was unclear and these often overlapped each other. A confused situation in revising and creating new laws allowed various interest groups, whether it be druggists, the pharmaceutical industry, or sickness funds, to reinforce their position at the expense of the disunited and conservative pharmacy profession. Being unable to assert themselves in their own field for legislative reasons, the well-qualified new generation of pharmacists realized their...

Autodidaktický test 3/2013

Prakt. lékáren. 2013; 9(3): 150-151