Jaký má vlastně smysl lékárnický slib?

prof. MUDr. Marta Munzarová, CSc.

Prakt. lékáren. 2015; 11(2)  

Advances in pharmacotherapy of pain

Marek Hakl

Prakt. lékáren. 2015; 11(2): 52-53  

In recent years, new active substances, dosage forms of previously known agents as well as new combinations of drugs have emerged in the field of pharmacotherapy of pain. Among active substances, a new molecule in the class of opioids has been encountered after more than 30 years. The new substance is tapentadol, a μ-opioid agonist capable of norepinephrine reuptake inhibition in the CNS. In the field of nonopioid analgesics, aceclofenac – a selective COX-2 inhibitor – has been newly introduced to the Czech market. In terms of treating cancer-related breakthrough pain, transmucosal fentanyls with an ultra-rapid onset of action...

New knowledges about functions of vitamin D

Petr Hrdý, Pavel Novosad

Prakt. lékáren. 2015; 11(2): 54-57  

Vitamin D is one of the lipophil vitamins, which one is necessary for correct structure and function of the skeleton. The lowered saturation of vitamin D plays an important role in immunity disorders, cardiovascular diseases and oncological too. Reduced level of vitamin D is an important risk factor of fall and fracture at older patient. On this hazard takes part osteoporosis and decrease of function and quantity muscular masses, so called sarcopenia. Sufficient supplementaton of vitamin D is one of the pharmacological goals in care of patient with frailty syndrome. One of the most important factor makes possible this reversibility is the vitamin...

Colitis due to Clostridium difficile - a severe contemporary epidemic

Pavel Polák, Petr Husa

Prakt. lékáren. 2015; 11(2): 58-60  

Colitis due to Clostridium difficile is within the past decade cause of epidemics worldwide and raising prevalence is being reported. Geriatric patients with numerous comorbidities who were repeteadly hospitalized and recently treated with broad-spectrum antibiotics are mostly affected. Treatment with aminopenicillins, cefalosporines, fluorochinolones and lincosamides is therefore of great concern. The disease may be treated either with vancomycin (orally), metronidazole or fidaxomicine. Fecal microbiota transplantation may be used in recurrent disease. The authors presentbasic informations about this severe condition and its treatment.

Bipolar disorder - a minimum for pharmacists

Eva Češková

Prakt. lékáren. 2015; 11(2): 61-63  

Bipolar disorder (BD) is a severe, mainly reccurent, multifactorial mental illness. Ĺithium with its antimanic, antidepressive, antisuicidal, prophylactic and neuroprotective properties has remained a major treatment of BD. In acute mania lithium, valproate, and several atypical antipsychotics in the monotherapy or combination with mood stabilizers are first-line treatments. For the management of bipolar depression, lithium, lamotrigine, and quetiapine monotherapy, as well as olanzapine plus selective serotonin reuptake inhibitor (SSRI), and lithium or valproate plus SSRI/bupropion remain first-line options. Still, the use of antidepressants...

Medicinal plants in prostatic problem treatment

Lenka Tůmová

Prakt. lékáren. 2015; 11(2): 68-70  

The article describes medicinal plants and natural matters used in the treatment of prostatic complaints. Potentially effective medicinal plants for these problems are also mentioned. The mechanism of their activity, side effects and notice on possible interactions with other medication are also explained.

Zaujalo nás na semináři Aesculap 2015

Rozhovor s doc.MUDr.Milošom Jeseňákom, PhD., MBA

Prakt. lékáren. 2015; 11(2): 71-73  

Insulin in Czechoslovakia

Jindřiška Krejčová, František Dohnal

Prakt. lékáren. 2015; 11(2): 74-77  

The aim of the article is an effort to capture the historical development of insulin production in Czechoslovakia. Information has been obtained mainly from two czech journals: „Časopis lékařů českých“ (published since 1862) and „Praktický lékař“ (published since 1921). At first, imported insulin appeared on the market in Czechoslovakia; insulin injections or substances from which insulin was prepared. Production of insulin was dealt with fivecompanies in years 1923- 1945, then the insulin was produced just by one company „Léčiva“.

Individual counseling in community pharmacy - case report of geriatric patient

Jana Šolínová, Josef Malý

Prakt. lékáren. 2015; 11(2): 64-67  

Individual consultations in pharmacy provide a way to identify and solve drug-related problems (DRP). The aim of this geriatric patient case report is to present continuity of the management of DRP including difficulties accompanying the care providing. Several types of DRP were identified. Pharmacist`s interventions were accepted by both patient and doctors. Individual consultation helped to increase patient adherence to treatment and optimize the pharmacotherapy.

Autodidaktický test 2/2015

Prakt. lékáren. 2015; 11(2): 78-79