Historia nova vel repetens?

PharmDr. Jan Babica, Ph.D.

Prakt. lékáren. 2015; 11(3)  

Pollen allergy

MUDr.Božena Kalabusová

Prakt. lékáren. 2015; 11(3): 86-88  

Article describes causes, symptoms and therapy of pollen allergy.

Paracetamol (acetaminophen) - new data, risk of overdose, intoxication and coping with it

MUDr.Mgr.Jiří Hodis, Ph.D.

Prakt. lékáren. 2015; 11(3): 90-92  

Acetaminophen (paracetamol) is well known and one of the most used analgesics and antipyretic since 1893 with very good toxicity profile. Nevertheless the toxicity of acetaminophen (in Europe called paracetamol) is not negligible. The review assumes the new facts about mechanism of action, toxicity, toxicity risk stratification and toxicity therapy protocols with prevention.

Co-analgesics - the optimal choice and indication

PharmDr.Jitka Rychlíčková

Prakt. lékáren. 2015; 11(3): 93-95  

Co-analgesics are a diverse group of drugs that includes anticonvulsants and antidepressants, and others (local anaesthetics, bisphosphonates, calcitonin, muscle relaxants, corticosteroids, spasmolytics, benzodiazepines). They can be used at any step of the WHO ladder alone or in combination with other analgesics. Correct choice of co-analgesics is summarized in the following text. Determination of the pain etiology is the first step. Carbamazepin appears to be effective in paroxysmal neuropathic pain, pregabalin and gabapentin are drugs of choice in painful polyneuropathy, including diabetic neutopathic pain, tricyclic antidepressants can...

Persons at risk for diabetes mellitus in the pharmacy

Josef Malý, Helena Marešová

Prakt. lékáren. 2015; 11(3): 96-99  

The high prevalence of diabetes mellitus, substantial costs associated with treatment of late complications of this disease and still a considerable proportion of persons who fail to be timely or properly treated, offer possibilities for pharmacists involvement in diabetes care. This report aims to specify the measures and procedures used in the early detection of diabetes mellitus with an emphasis on the possible involvement of the pharmacists.

Overview of the effects and safety of the use of natural medicines during pregnancy and lactation - part 4

doc.PharmDr.Lenka Tůmová, CSc., Mgr.Lenka Holcová

Prakt. lékáren. 2015; 11(3): 103-106  

The subscription continues in previous paper „Danger of medicinal plants used in pregnancy and breast-feeding period“. Therapeutic use, side effects and categorization of safety drug use in pregnancy and in breast-feeding period are shown in the form of tables in individual drugs (alphabetic order-letter E-G). There are also mentioned the results of animal study models and human models.

Glucose pellets in preventing hypoglycaemia

PharmDr.Aleš Franc, Ph.D., doc.Mgr.Jan Muselík, Ph.D., MUDr.David Neumann, Ph.D., Mgr.Dana Sabadková

Prakt. lékáren. 2015; 11(3): 100-102  

Hypoglycaemia occurs as a result of disproportion between the antidiabetic administered, energy expenditure, and the amount of saccharides used. The majority of hypoglycaemic events can be predicted since they result from erroneous treatment decisions. However, some hypoglycaemias arise from the treatment options, and can hardly be managed with lifestyle measures. The aim is to develop a dosage form containing pellets with delayed glucose release. The dosage form comprises an inert core in the form of a pellet containing glucose coated with a membrane that releases glucose with a time delay when passing through the gastrointestinal tract. According...

Spring fever and detoxification of human body

Mgr.Markéta Obrovská

Prakt. lékáren. 2015; 11(3): 107-110  

Spring is often connected with specific type of tiredness – so called spring fever. Patients have an urge to cleanse their organism by body cleanse in this time. The article is focussed on possibilities of reduction of spring fever and how to strengthen the most strained detoxification organs of human body – liver, kidneys and bowels. Detoxification of body is not always benefitial. Risk groups include pregnant and breastfeeding women and chronic patients.

Jandouš's introduction to formulation

RNDr.Pavel Drábek

Prakt. lékáren. 2015; 11(3): 111-113  

The Prague pharmacist Dr. A. Jandouš helped to develop the Czech academic literature in the second half of the 19th century. In addition to original papers from pharmacy and numerous reports from foreign journals, he also wrote three handbooks. The third one deals with the fundamentals of formulation and was intended for pharmacists and medical students. Its subject matter is divided according to dosage forms. The text is supplemented by practical examples and tables. It is also the first publication from the field of galenic pharmacy in this country.

Autodidaktický test 3/2015

Prakt. lékáren. 2015; 11(3): 114-115