Nemocniční lékárenství v roce 2017

PharmDr. Petr Horák

Prakt. lékáren. 2017; 13(2)  

Pharmacotherapy of irritable bowel syndrome

Jan Juřica, Radek Kroupa

Prakt. lékáren. 2017; 13(2): 52-59 | DOI: 10.36290/lek.2017.005  

Irritable bowel syndrome is one of the most frequent functional diseases of gastrointestinal tract. Among typical symptoms there are GIT dyscomfort, abdominal pain, bloating, and change in stool consistency and/or stool frequency. Pharmacotherapy is supplementary to dietary and regime approaches and is truly symptomatic, but it often brings patients significant relief from symptoms. This article is pharmacological review of groups of drugs used in the treatment of irritable bowel syndrome. It introduces mechanisms of action, particularities of pharmacokinetics of spasmolytics, laxatives, antidiarhoics, prokinetics, antibiotics and psychotropic...

Drug-induced photosensitivity

Hana Bakhouche, Martin Šíma, Ondřej Slanař

Prakt. lékáren. 2017; 13(2): 60-62 | DOI: 10.36290/lek.2017.006  

Data suggest that more than 300 drugs are reported to be photosensitizers. However, the effect of only a few drugs have been well described. It seems that many photosensitive reactions are underdiagnosed due to the difficulty to prove the relationship between the drug and sun exposure. It is important to clarify this relationship to timely treat patients or better to take adequate measures to prevent adverse effects.

New classification of venoactive drugs

Veronika Slonková

Prakt. lékáren. 2017; 13(2): 63-66  

Chronic venous disease (CVD) represents a major health problem, as its prevalence is high – up to 84% of population including patients with clinical stage C0 (Vein Consult Programme, 2012). Venoactive drugs (VAD) are a basic conservative treatment of CVD. New guidelines for the treatment of CVD were published in 2014. There are changes in classification of VAD based on their safety and efficacy. Micronized purified flavonoid fraction (MPFF) is now the only VAD with grade 1B (a strong recommendation based on moderate evidence). Rutosides, red wine leaves extracts, calcium dobesilate, horse chestnut seed extract and Ruscus extract are all...

New medicinal substances in extemporaneous prescription, part 15 – polihexanide

Jan Hašek

Prakt. lékáren. 2017; 13(2): 71-74 | DOI: 10.36290/lek.2017.007  

Polihexanide is an antiseptic agent with a broad spectrum of activity against bacteria, yeasts and some types of fungi. It is a colorless and non-toxic substance which is very well tolerated by tissues and is not absorbed due to its polymer structure. The main application of polihexanide is used in wound healing. This article informs about the properties and possibilities of using polihexanide in the extemporaneous preparation in the pharmacies. For the preparation of drugs, polihexanide as a 20% solution is newly available as a pharmaceutical substance. In addition to foreign standardized and non-standardized formulas are also presented in the...

Photoprotective products for children

Naděžda Vojáčková

Prakt. lékáren. 2017; 13(2): 79-82  

Photoprotection in children is of major importance. Emphasis is placed on physical photoprotection that includes clothing, hats, sunglasses, and shade. Photoprotection using creams with UV filters is intended for children over six months of age. Products with a broad spectrum of protection are recommended, which are water-resistant, with an SPF factor 50+, with a predominance of physical filters, photostable, dispersible, and cosmetically acceptable with a low irritation potential.

Travel health kit – what medication you should take with yourself while travelling and how to store the medication?

Markéta Obrovská

Prakt. lékáren. 2017; 13(2): 75-78 | DOI: 10.36290/lek.2017.008  

Travel health kit should be equipped functionally. It is also necessary to have the smallest size of this health kit. The article is meant as a clue what is good to have in a travel health kit according to demands of traveler. It also describes how to store medication which is packed in the kit.

OTC drugs to treat infections of the vulva and vagina view of outpatient gynecologist

Hana Kosová

Prakt. lékáren. 2017; 13(2): 84-88 | DOI: 10.36290/lek.2017.010  

Inflammation of the vulva and vagina is the most common gynecological problem in outpatient gyncologists. There is a difficult ecosystem of bacterias in vagina, which protects the vagina, but in case of disruption of this system appear difficulties and illness. The disease, the course, etiology and treatment also varies depending on the level of sex hormones whose levels significantly influences the composition of vaginal mikrobionty. Treatment is carried out by many women in the mode of self-treatment, where most of the affected women use antifungal preparations, which can be buied in pharmacies without prescribtion. Common outpatient gynecologist don...

Skin problems in infants and toddlers I.

Klára Bechná

Prakt. lékáren. 2017; 13(2): 89-92 | DOI: 10.36290/lek.2017.011  

Children’s skin is a highly sensitive organ, so it is not surprising that skin rash and eczema are among common complaints in the very early age of life. The article presents a review of the specific features of children’s skin that need to be understood so that skin problems in infants can be seen in a broader context. The first part of the article will deal with the characteristics and self-treatment of the most common non-infectious skin problems in infants and toddlers (intertrigo, irritant contact dermatitis, and skin rash associated with the action of sweat and sebaceous glands). The second part of the article will further discuss...

Autodidaktický test 2/17

Prakt. lékáren. 2017; 13(2)