Sekce technologie léků

doc. PharmDr. Kateřina Kubová, Ph.D.

Prakt. lékáren. 2017; 13(4): 147  

Drug induced movement disorders – basics for pharmacologists

Marek Baláž, Tomáš Kašpárek

Prakt. lékáren. 2017; 13(4): 151-155 | DOI: 10.36290/lek.2017.021  

Drug induced movement disorders may appear after number of pharmacological treatments. Dopaminergic-treatment relatedchorea in Parkinson’s disease and tardive dyskinesia are the ones most well described.Determination of the type of hyperkinesia is very important for the diagnosis of drug-induced movement disorders, as the treatmentsdiffer across the various clinical phenomena. Treatments are based on tapering of dose or discontinuation of offendingdrug but may include also targeted pharmacotherapy, botulinum toxin or deep brain stimulation.

Current treatment options for cough in children

František Kopřiva

Prakt. lékáren. 2017; 13(4): 156-160  

Cough is the most frequent symptom in children for which parents seek medical attention for their child. Depending on its duration,cough can be divided into acute (< 3 weeks), prolonged (3–4 weeks), and chronic (> 4–6 weeks). Most children with acutecough have viral upper respiratory tract infection. The article presents a review of therapeutic active substances and medicinalproducts in treating dry as well as productive cough in children.

Application devices in diabetic patients’ treatment

Kateřina Štechová

Prakt. lékáren. 2017; 13(4): 162-165 | DOI: 10.36290/lek.2017.022  

In the treatment of diabetic patients (suffering from type 1 and type 2 diabetes as well as from other types of diabetes) drugswhich must be administered via parenteral way are frequently used. These drugs are applied subcutaneously. To this group notonly insulin belongs. GLP-1 analogues and glucagon (e.g. an emergency medication for hypoglycaemic coma) are given subcutaneouslyas well. The administration of these drugs must be precise, gentle, simple and safe to prevent the risk of infection.Application devices used to deliver these drugs must fulfil these criteria but esthetical viewpoint should be taken into account aswell. These devices are disposable...

Over-the-counter drugs for self-treatment of pain

PharmDr. MVDr. Vilma Vranová, Ph.D.

Prakt. lékáren. 2017; 13(4): 176-179  

An overview of over-the-counter drugs for self-treatment of pain is presented as a follow-up to an article in the previous section(Prakt. lékáren. 2017; 13(4): 173–175).

Doplňky stravy obsahující extrakt vrbové kůry vs. léčebné účinky kyseliny acetylsalicylové

Prakt. lékáren. 2017; 13(4)  

Reakce na článek „Léčivé rostlinné drogy tradiční čínské medicíny a možnosti jejich uplatnění“

PharmDr. Jakub Treml, Ph.D.

Prakt. lékáren. 2017; 13(4): 165  

Gastroesophageal reflux disease – risk drugs and treatment options

Jitka Rychlíčková

Prakt. lékáren. 2017; 13(4): 169-172 | DOI: 10.36290/lek.2017.065  

Heartburn, non-cardiac chest pain and regurgitation are symptoms of gastroesophageal reflux. The main cause of reflux seemsto be transient relaxation of the lower esophageal sphincter. The prolonged period of contact between acidic gastric content andesophageal mucosa is the cause of above mentioned symptoms. Pharmacological options to affect lower esophageal sphincterpressure, acidity of gastric content are summarized in order to select the best therapy depending on the nature of the disordersdescribed by the patient, his co-morbidities and co-medications and the possible adverse drug effects.

Self-treatment of pain

Vilma Vranová

Prakt. lékáren. 2017; 13(4): 173-175 | DOI: 10.36290/lek.2017.025  

In the treatment of pain, pharmacies are often the place of first contact between a patient and a healthcare professional. Given thegrowing trend of self-treatment, there is a growing risk of overdose, drug interactions, and adverse effects of pain management.This increases the importance of the pharmacist as an expert who must recommend proper analgesic doses and draw attentionto the risks of duplicate therapy. Advice on appropriate lifestyle measures or nonpharmacological methods, such as the use ofheat, can aid in successfully managing pain.

Ergotamine-induced coronary artery spasm

Andrea Carbolová, Jan Novák

Prakt. lékáren. 2017; 13(4): 166-168 | DOI: 10.36290/lek.2017.024  

For many years, ergotamine has been used for the acute treatment of migraine. In most patients, ergotamine is well tolerated,but also has potential for many side effects. It has been reported, that ergot alkaloids can provoke coronary artery spasm, whichis often associated with ischemic electrocardiography changes and angina pectoris.In the present report, we describe a case involving woman with unclear diagnosed migraine who experienced acute coronarysyndrome most probably because of therapy with ergotamine.To add the knowledge to submitted report, an information about phenomenon of egrotamine overuse headache and aboutcauses of coronary vasospasm...

Autodidaktický test 4/17

Prakt. lékáren. 2017; 13(4)