Populismus - cui prodest ?

doc. PharmDr. Alexandr Hrabálek CSc

Prakt. lékáren. 2009; 5(2): 51  

Paediatric skin care

MUDr. Renáta Kolářová, doc. MUDr. Peter Koliba CSc

Prakt. lékáren. 2009; 5(2): 59-63  

The structure of child skin changes with the child's age with each period having specific features; therefore, skin care in children requires an individual approach which takes into account the particular periods of childhood. Complex therapy for skin diseases in children is taken care of by a specialist, a paediatric dermatologist. The aim of the paper is to clarify important facts concerning the uniqueness of child skin and to highlight the treatment of the most common dermatoses that can be encountered in paediatric patients.

Lower urinary tract infections, urinary tract infections in pregnancy and lactation

MUDr. Michaela Matoušková, doc. MUDr. Tomáš Hanuš CSc

Prakt. lékáren. 2009; 5(2): 64-69  

Both urinary and respiratory infections significantly influence the prescribing of antimicrobial agents and, in a feedback manner, lead to developing resistance to them. In most economically developed countries, urinary tract infections (UTIs) are the second leading type of infections. A reasonable administration of empiric as well as targeted treatment with antimicrobial agents may affect therapeutic costs and potential complications and their treatment. Undertreated or untreated infection is likely to have a prolonged or chronic course, which is also the case with self-therapy based on TV commercials. In addition to higher diagnosis and treatment...

Pharmacology of insomnia

PharmDr. Kateřina Vašutová

Prakt. lékáren. 2009; 5(2): 70-75  

Sleep difficulties affect nearly one half of the population of developed countries. The treatment of these difficulties is not simple and requires a complex approach to individual patients. In addition to pharmacotherapy, daily routine measures including adherence to the principles of sleep hygiene and psychotherapy are of major significance. Pharmacists are the first within the healthcare system who come into contact with these patients. It is therefore essential that pharmacists be very well acquainted not only with insomnia treatment but also with its possible causes and can, based on their expert knowledge, recommend the patient an appropriate...

Biological therapy of rheumatic diseases

MUDr. Jiří Štolfa

Prakt. lékáren. 2009; 5(2): 76-82  

The ineffectiveness of „disease-modifying“ drugs in a proportion of patients with inflammatory arthropathies and inconclusive results of studies investigating radiological progression have accelerated the efforts to develop new, more effective pharmaceuticals with an aim to affect not only clinical activity but also radiological progression. The development of these new pharmaceuticals is based on the knowledge of the key roles of T and B lymphocytes and cytokines produced by activated immunocompetent cells in the pathogenesis of inflammatory arthropathies. The most significant cytokines include tumor necrosis factor alpha (TNFα),...

Rosuvastatin

doc. MUDr. Tomáš Štulc, Ph.D, prof. MUDr. Richard Češka, CSc

Prakt. lékáren. 2009; 5(2): 55-58  

Rosuvastatin is the latest member of the drug class of statins to have been introduced to our market. Of the available statins, it works best at decreasing the LDL cholesterol – at a maximum dose, it has a slightly higher effect than the so far most effective atorvastatin; it also increases the HDL cholesterol significantly more compared to the other statins. In terms of treatment safety, it is of importance that rosuvastatin is not metabolized by cytochrome P450 and is therefore associated with a lower risk of drug interactions. The efficacy and safety of rosuvastatin have been tested in several clinical studies that showed regression of...

Preparation of AIO parenteral nutrition for paediatrics and neonatology

PharmDr. Michal Janů, doc. PharmDr. Ruta Masteiková CSc

Prakt. lékáren. 2009; 5(2): 83-86  

The preparation of parenteral nutrition for neonatology and paediatrics follows the mandatory rules and regulations for aseptic preparation of drugs and for the quality, safety, and efficacy of the AIO system for parenteral nutrition. The paper gives evidence of numerous differences in individual nutritional components, requirements for preparation, the monitoring of the compatibility of individual nutrients and stability of such a multicomponent system with an emphasis on the quality of fat emulsion. For a pharmacist, this area represents a unique opportunity to participate in both preparation and a multidisciplinary nutrition team, if only for...

Inhibition of α-amylase and α-glucosidase with natural substances

Mgr. Jan Martin Ph.D, doc. RNDr. Jaroslav Dušek CSc

Prakt. lékáren. 2009; 5(2): 92-95  

Human nutrition consists of three main components: saccharides, lipids, and proteins. Saccharides account for as much as 60 percent and most of this amount comes in the form of starches. By using enzymes (amylases and glucosidases), the digestive system breaks down this polysaccharide into glucose which is the basic source of energy for animal cells. The inhibition of amylases and glucosidases decreases the biological availability of glucose, thus reducing postprandial hyperglycaemia (elevated blood glucose after a meal). These inhibitors may play a significant role in diagnosing and treatment of diabetes and obesity. Substances having this effect...

Artificial milk nutrition of infants

MUDr. Pavel Frühauf CSc

Prakt. lékáren. 2009; 5(2): 88-90  

Artificial milk nutrition of infants – state of arts.

655 milionů EUR pro německou e-kartu

PharmDr. Martin Dočkal

Prakt. lékáren. 2009; 5(2): 101  

Zákaz cizího vlastnictví lékáren potvrzen

PharmDr. Martin Dočkal

Prakt. lékáren. 2009; 5(2): 99-100  

Historie parenterální výživy

PharmDr. Michal Janů, doc. PharmDr. Ruta Masteiková CSc

Prakt. lékáren. 2009; 5(2): 97-98  

K životnímu jubileu prof. PhMr. RNDr. Karla Paláta, CSc.

Prakt. lékáren. 2009; 5(2): 102  

Autodidaktický test 2/2009

Prakt. lékáren. 2009; 5(2): 96