Komunikace v lékárně

PharmDr. MVDr. Vilma Vranová

Prakt. lékáren. 2010; 6(4): 167  

Pharmacotherapy in reproductive medicine

doc.MUDr.Igor Crha, CSc.

Prakt. lékáren. 2010; 6(4): 173-176  

Approximately 15–20 % couples have problems with fertility. In the Czech Republic, more than 3 % of children are born after assisted reproduction techniques. Clomifen citrate is the basic substance for ovarian stimulation. Protocols with follicle stimulation hormone (FSH) and gonadoliberine (GnRH) analogues are used for assisted reproduction techniques (ART). Human chorionic gonadotropine (hCG) is used for eggs maturation. Progesteron is used for endometrium transformation and luteal phase support. Careful monitoring of ovarian stimulation decreases risk of possible complications.

Pigmentary disorders - treatment of melasma

MUDr.Kateřina Klauzová, MBA

Prakt. lékáren. 2010; 6(4): 177-180  

The type and amount of melanin synthesized by the melanocytes, and its distribution pattern in the surrounding keratinocytes, determines the actual color of the skin. Melanin forms through a series of oxidative reactions involving the amino acid tyrosine in the presence of the enzyme tyrosinase. Impaired metabolism or impaired distribution of melanin result in hyperpigmenation or depigmentation. Melasma (or chloasma) is a common disorder of cutaneous hyperpigmentation predominantly affecting sun-exposed areas in women. The pathogenesis of melasma is not fully understood and treatments are frequently disappointing and often associated with side...

Specific antifungals and their use in the therapy of selected diseases

PharmDr.Petr Horák

Prakt. lékáren. 2010; 6(4): 182-186  

The incidence of systemic fungal infections especially has been growing in last decades. It is related to the expansion of HIV/AIDS pandemic and also to the development of therapy of many diseases that affect immunity. It has resulted in the development of new drugs and new therapeutic classes, or changes in the administration and indications of formerly known drugs. Moreover, new therapeutic approaches have also been employed in the therapy of topical mycoses, and this article is devoted to them, too.

Enteral and parenteral phosphate replacement from a pharmacist's viewpoint

PharmDr.Michal Janů, MUDr.Eva Meisnerová, PharmDr.Jitka Dvořáková, doc.PharmDr.Ruta Masteiková, CSc.

Prakt. lékáren. 2010; 6(4): 187-189  

The phosphate anion is abundant in the body and is involved in numerous physiological processes, including storage of energy in highenergy bonds. Its regular intake in food is essential and, when there is a lack of its natural intake, early initiation of replacement with pharmaceutical products is important. Oral administration of phosphorus can be done by using food supplements, artificial enteral nutrition or extemporaneous solutions. Parenteral intake can be provided by using proprietary medicinal products or AIO formulations prepared extemporaneously, as well as by using concentrated infusion solutions of phosphate salts.

Prasugrel - a novel antiplatelet agent

doc.MUDr.Otto Mayer, CSc.

Prakt. lékáren. 2010; 6(4): 170-172  

Dual antiplatelet therapy with acetylsalicylic acid (ASA) and clopidogrel is the mainstay of treatment in patients with acute coronary syndrome (ACS) and following percutaneous coronary intervention (PCI). Despite the proven protective effect of this treatment, a significant proportion of patients remain unprotected by medication because neither ASA nor clopidogrel (Plavix, and others) are effective in all patients. Prasugrel (EFIENT) as another advancement in the group of thienopyridine antiplatelet agents represents a shift towards improved treatment in terms of a more reliable effect. The paper explains that this is mainly due to the more...

Recommended practices in care for chronic patients - insomnia consultancy

PharmDr.Jana Kubišová

Prakt. lékáren. 2010; 6(4): 200-206  

At present, consultation activity at the chemist´s is a quite readily advancing area of interest within provided pharmaceutical care. A pharmacist should be ready to communicate with a patient in order to gain important information about illnesses, pharmacoteraphy, life style, etc., and, based on his expert qualification, he should be able to review drug problems and other problems, and to propose their suitable solutions. This paper might represent certain instructions in the way of carrying out a consultation with an insomniac properly. Basic information on insomnia is the part of the paper.

Curcuma - therapeutic effects and possible interactions

doc.PharmDr.Lenka Tůmová, CSc., Mgr.Libuše Zatloukalová

Prakt. lékáren. 2010; 6(4): 209-211  

The present article highlights significant preventive and/or curative effects of Rhizoma curcumae, or curcumin, that have been found in experimental animal models in a number of conditions, including atherosclerosis, cancer, diabetes, respiratory, hepatic, pancreatic, intestinal and gastric diseases, neurodegenerative conditions and eye diseases. It also deals with possible interactions of this drug with other medications.

New medicinal substances in extemporaneous prescription, part 2 - dexpanthenol

PharmDr.Jan Hašek

Prakt. lékáren. 2010; 6(4): 192-197  

The present article deals with dexpanthenol as a pharmaceutical substance that is used in the treatment of skin and mucosal conditions and can be used to prepare medicinal products in a pharmacy. Dexpanthenol is a universal as well as very safe drug being used in otorhinolaryngology and, in particular, dermatology. The paper describes the properties, mechanism of action and use of dexpanthenol not only as a drug promoting cellular metabolism, but also deals with the role of the substance as a component of the natural hydrating factor, or moisturizer, in a wider context during adjuvant therapy for atopic dermatitis. Also, galenic properties...

Snoring

PharmDr.Kateřina Vašutová

Prakt. lékáren. 2010; 6(4): 207-208  

Snoring occurs in 20–40 % of the population with men being more commonly affected. Snoring is accompanied by producing very unpleasant sounds. It not only adversely affects social life, but also poses health risks, particularly when accompanied by obstructive sleep apnoea syndrome.

Používání elektronického receptu se v USA výrazně zvýšilo

PharmDr. Martin Dočkal

Prakt. lékáren. 2010; 6(4): 212  

Lékárníky již po čtvrté přilákal do Olomouce pestrý program a špičkoví přednášející

Mgr. Jitka Strouhalová

Prakt. lékáren. 2010; 6(4): 213  

Prasugrel - nový protidestičkový přípravek Srovnání s klopidogrelem - Komentář ke článku (Prakt. lékáren. 2010; 6(4): 170-172)

doc.PharmDr.Martin Doležal, Ph.D.

Prakt. lékáren. 2010; 6(4): 172  

Inhibitory protonové pumpy. Inhibitory protonové pumpy jako volně prodejné léky z pohledu lékárníka

PharmDr. Pavel Grodza

Prakt. lékáren. 2010; 6(4): 190  

Autodidaktický test 4/2010

 Redakce

Prakt. lékáren. 2010; 6(4)