Jaký ten rok vlastně byl?

PharmDr. Pavel Grodza

Prakt. lékáren. 2011; 7(6): 251  

Hyperuricaemia and gout: basic facts

David Suchý

Prakt. lékáren. 2011; 7(6): 259-260  

Gout management has three key goals. Treatment of acute gout flares, prophylaxis against acute gout flares and long term treatment of chronic gout. In last years, progress has been made in the better utilisation of old drugs and the development of new agents for the treatment of gout. Febuxostat is a new non-purine selective xanthioxidase inhibitors that is more potent than allopurinol. Its efficacy was confirmed in phase III trials, where significantly more febuxostat treated patients met the primary endpoint (serum urate < 360 μmol/l), febuxostat was more effective in subset of patients with impaired renal function. Long term extension...

Pharmacotherapy of alcohol dependence

Lukáš Láznička

Prakt. lékáren. 2011; 7(6): 262-264  

Alcohol dependence is a progressive chronic disorder. Treating alcoholism involves several stages. The initial stage deals with acute withdraw or delirium. Later stages attempt to maintain abstinence combine both pharmacotherapy and psychotherapy. In clinical trials has been shown the effect of disulfiram, acamprosat, naltrexon and serotonergic agents and their combinations.

How to manage pain quickly

Pavlína Nosková

Prakt. lékáren. 2011; 7(6): 266-270  

Rational treatment management of acute pain enable to prevent chronicity transition. The key is use of all available pharmacotherapy methods in already common pain caused by locomotive apparatus, headache, teeth, dysmenorhea etc., and with regard to safety and possible adverse events of analgetics. Lack of information in patients in OTC products, mainly in non-steroid antirevmatics leads to its abusus, avoidable hospitalization, and sometime even to death. Principles of pain treatment are available, and regularly updated in Methodology guidelines for pain treatment SSLB.

The most common upper respiratory tract infections in children

Katra Rami

Prakt. lékáren. 2011; 7(6): 272-275  

Upper respiratory tract infections are very common in childhood with some, such as otitis media, having a significant prevalence; it is reported that up to 84 % of individuals under three years of age experience at least one episode of middle ear inflammation. Other conditions, such as acute epiglottitis, are very rare but extremely dangerous and require transport to a specialized centre where emergency airway management is available. The majority of catarrhs of the upper respiratory tract are infections that require basic diagnostic knowledge and strategies.

Febuxostat

David Suchý

Prakt. lékáren. 2011; 7(6): 256-257  

Febuxostat is a new non – purine selective xanthioxidase inhibitors that is more potent than allopurinol. Its efficacy was confirmed in phase III trials, where significantly more febuxostat treated patients met the primary endpoint (serum urate < 360 μmol/l), febuxostat was more effective in subset of patients with impaired renal function. Long term extension studies confirmed the efficacy and tolerability of febuxostat. In patiens with target uric acid level, the incidence of gout flares fell continually and tophi resolved in more than 50 % of patiens. The incidence of averse events during febuxostat treatment is probably similar...

Licorice - therapeutic effects and possible interactions

Lenka Tůmová

Prakt. lékáren. 2011; 7(6): 286-287  

The present article describes the active compounds in licorice root, their therapeutic effects, dosage, side effects and possible interactions of this drugs with other medications. Also is reported the danger of pseudoaldosterism and hypocalemia after long-term use of this drug.

Extemporaneously prepared pediatric dosage forms - part 1

Sylva Klovrzová

Prakt. lékáren. 2011; 7(6): 276-278  

This article summarizes possibilities of small scale preparation of non-sterile dosage forms with systemic effects designed for pediatric population. Suitability of dosage form depends on route of administration, age of children and physical-chemical and biopharmaceutical properties of drug substance. If the active pharmaceutical ingredient (API) is not available as a raw material, it is possible, under certain circumstances, to modify the licensed product to suitable form for pediatric administration with required dosage of API. The pharmacist is responsible for quality, stability and content of drug during shelflife.

The possibilities of self-treatment in selected gastrointestinal tract disorders in pregnant and nursing women

Martin Doseděl, Josef Malý, Martin Procházka

Prakt. lékáren. 2011; 7(6): 280-285  

The aim of the paper is to describe the possibilities of self-treatment of gastrointestinal tract (GIT) disorders in pregnant and nursing women. Pregnant and nursing women are among those in whom self-treatment is associated with a greater risk than in the general population. The pharmacist and pharmaceutical assistant play an irreplaceable role in the system of self-treatment and should guarantee effective and safe self-treatment. The paper deals with selected gastrointestinal tract symptoms suitable for self-treatment and outlines the possibilities of self-treatment in pregnancy and breastfeeding. Particular attention is paid to over-the-counter...

Infant nutrition - recommendation 2011

Pavel Frühauf

Prakt. lékáren. 2011; 7(6): 288-289  

Introducing solids (rather than formula) before six months may not significantly affect risk of infection. By contrast, exclusive breast feeding to six months raises concerns about higner risk of food allergies, iron deficienty anemia and coeliac disease.

Západočeská metropole úspěšně hostila 27. lékárnické dny

Martin Dočkal

Prakt. lékáren. 2011; 7(6): 291  

40. mezinárodní kongres pro dějiny farmacie

Martina Lisá

Prakt. lékáren. 2011; 7(6): 292  

Febuxostat

Martin Doležal

Prakt. lékáren. 2011; 7(6): 258  

Autodidaktický test 6/2011

Prakt. lékáren. 2011; 7(6): 293-294