Slovo úvodem

PharmDr. Jana Šolínová

Prakt. lékáren. 2015; 11(4)  

Modern trends in the ovarian stimulation

Pavel Trávník

Prakt. lékáren. 2015; 11(4): 123-125  

The ovulation stimulation is essential procedure for most methods of reproductive medicine. Modern trends in stimulation lie in the individualized stimulation, the safety enhancement, the application facilitation including the depot injections use, and enabling the treatment of the patients, requiring special stimulation procedures, such as the polycystic ovarian syndrome and tumour risk. safety.

Enteral nutrition - overview and use in clinical practise

Eliška Bohatcová

Prakt. lékáren. 2015; 11(4): 127-132  

Nutrition of patients was long overlooked and underestimated field of medicine. It has been clearly shown that malnutrion is an independent risk factor for improving patient morbidity, prolongs existing hospitalization, increases mortality and economically increases the cost of treatment. Now there are available many products on the market intened for enteral nutriton that can, if properly indicated, significantly improve patient´s nutrition state, increase his quality of life and help recovering during hospitalisation. The aim of this article is to give a basic overview of products that are available on the czech market and to give instructions...

Vitex agnus-castus - active substances and medicinal effects

Zdeňka Navrátilová

Prakt. lékáren. 2015; 11(4): 138-140  

Vitex agnus-castus (chasteberry, monk´s pepper) is a shrub or small tree originating from Southern Europe and Western Asia. It has been used for centuries to treat many hormone-related gynecological conditions. The article summarizes knowledge of medicinal use of this plant, therapeutic effects and possible interactions and side effects.

Cellulose derivatives in extemporaneous preparation

Eva Šnejdrová, Denisa Sajková, Ivana Černá

Prakt. lékáren. 2015; 11(4): 133-136  

Cellulose derivatives, gelatin, and carbomers are the most used excipients for extemporaneous preparation of mucilages and gels. This article discusses the cellulose derivatives. The pharmacopoeial and best known brand names, the essential physico-chemical properties, viscosity values of 2 % water dispersions, dispersion techniques are specified, also some examples of the wrong prescriptions still used in practice are mentioned. Cellulose derivatives should be named according the pharmacopoeia, not using the brand name, and delivered to the pharmacy with a declared value of viscosity, furthermore other characteristics important for compounding...

How are new drugs developed

Lenka Součková, Hana Kostková, Regina Demlová

Prakt. lékáren. 2015; 11(4): 144-147  

The process of research and development of new drugs is very time and financially demanding. Since the start of research to placing the new drug on the market the development of the one new drug takes 12–15 years and the average cost is worth about – 2,6 billions. USD. The constantly increasing time and financial demand is closely linked with efforts to be marketed safer and more effective drugs and associated requirements, such as detailed and prolonged preclinical safety testing. The individual successive stages of drug development (in silico, in vitro, in vivo and in homo) are described in the article. The article discusses the...

Setkání s čínskými farmaceuty

prof. PharmDr. Martin Doležal, Ph.D.

Prakt. lékáren. 2015; 11(4): 148  

Over-the-counter medicines for headaches - proper selection and possible risks

Ingrid Niedermayerová

Prakt. lékáren. 2015; 11(4): 141-143  

Over-the-counter (OTC) analgesics are divided according to their clinical effect structure to analgesics – anti-inflammatory drugs (ibuprofen, naproxen, diclofenac, dexketoprofen) and analgetics–antipyretics (acetylsalicylic acid, paracetamol, propyphenazone), and according to the number of substances to simple and combined analgesics. OTC analgesics are used in the treatment of migraine, tension- type headache and minor secondary headaches. The choice of the drug depends on the intensity of pain, the presence of associated symptoms, other used medications (warfarin, aspirin, other nonsteroidal anti-inflamatory drugs, corticosteroids,...

Autodidaktický test 4/2015

Prakt. lékáren. 2015; 11(4): 149-150