Slovo úvodem

PharmDr. Martin Kopecký, Ph.D.

Prakt. lékáren. 2020; 16(2): 59  

Farmacotherapy of headache, mainly migraine

Irena Novotná

Prakt. lékáren. 2020; 16(2): 63-66  

Headache is one of the most common disorders encountered by nearly everyone. It is primarily divided into primary, where the most typical variety is migraine and its forms, and secondary, where headache is a symptom of another illness and it accompanies this illness. After the illness is cured, headache most often disappears. Headaches are distinguished in detail according to International Headache Society classification. In a daily practice of a physician or farmacist, the most important classification is to primary and secondary headache. According to anamnesis, after excluding possible secondary reasons and with normal results of common support...

Antihistamines indicated for systemic and topical treatment

Veronika Kunešová

Prakt. lékáren. 2020; 16(2): 67-73 | DOI: 10.36290/lek.2020.010  

Antihistamines represent a category of drugs that inhibit the binding of histamine to its H1 receptors and thereby affect its local action, do not block or reduce histamine release. Antihistamines are considered the first line of choice for allergic reactions, but their clinical potential is much broader. Their main indication is allergic rhinitis, allergic conjunctivitis, urticaria, angioedema, allergic rash or anaphylaxis. This group of drugs belongs to the category of therapeutics used in clinical practice for more than half a century and yet in some drugs we do not know their pharmacokinetic and dynamic parameters in details. In many cases, the...

The most common bacterial skin infections in children

Štěpánka Čapková

Prakt. lékáren. 2020; 16(2): 74-78 | DOI: 10.36290/lek.2020.011  

Bacterial skin infections are among the most common dermatological conditions for which patients present to paediatricians and skin specialists. However, there may be some delay before one receives an appointment with a dermatologist, a general paediatrician is not always readily available, and emergency medical service for children is usually remote from the sick child's place of residence. Given the dense network of pharmacies with opening times into the evening and some of them even on Saturdays and Sundays, concerned parents with their child often attend the nearest pharmacy, consulting the origin and possible self-treatment of skin disease with...

Problems of vaccination during SARS-CoV-2 pandemic with emphasis on the children

Vanda Boštíková

Prakt. lékáren. 2020; 16(2): 79-82 | DOI: 10.36290/lek.2020.012  

Vaccination protect against an infectious disease, as well as to stop the spread of the infection. At the individual level, a specific immune response is created, at the population level, herd immunity is created. Recently, vaccines are available for more than 25 different diseases, constructed on at least six different principles. Due to the effects of the pandemic spread of the new coronavirus SARS-CoV-2, the development of a vaccine has become one of the key objectives in the fight against this respiratory infectious disease. A secondary consequence of the pandemic is the postponement of non-urgent medical procedures, including vaccinations. However,...

Inflammatory bowel disease and the importance of probiotics treatment

Barbora Pipek

Prakt. lékáren. 2020; 16(2): 83-86  

Crohn´s disease and ulcerative colitis are inflammatory bowel diseases, whose cause is not clear. We expected, that genetic and external factors participate in to their origin. The treatment of Crohn´s disease and ulcerative colitis is complicated and aminosalicylates, corticosteroids, immunosuppressants, and recently also biological therapy are the basis of the treatment of inflammatory bowel diseases (IBD). Probiotics are living microorganisms of the human origin, that can influence human health, if they are used in sufficient quantities. Their position in IBD treatment is not dominant, but they are important in the long-term treatment of ulcerative...

Selected species of antidiabetic plants and mushrooms and their use in treatment of diabetes mellitus

Zdeňka Navrátilová

Prakt. lékáren. 2020; 16(2): 88-93 | DOI: 10.36290/lek.2020.014  

Diabetes mellitus is a chronic metabolic disease which is characterized by hyperglycemia. Currently it is one of the major health problems in the world and its incidence is increasing. Hyperglycemia is caused either lowered or no insulin secretion or by peripheral tissues resistance to its effects. Uncompensated diabetes with inadequate regulation of the blood sugar imposes serious consequences for health, such as retinopathy, nephropathy, cardiovascular diseases, etc. Prediabetes is a stage which usually converts to diabetes mellitus, it´s characterized by above normal blood glucose levels or having impaired glucose tolerance. In prediabetes and type-2...

Phytotherapy in the infertility treatment

Lenka Sobková

Prakt. lékáren. 2020; 16(2): 94-96 | DOI: 10.36290/lek.2020.015  

If there are troubles by conceiving it is important find the cause of the problem. For many of them, phytotherapy offers effective and save options. The circumstances of modern life, including stress, also interfer with hormonal levels. In these cases can phytopharmaceuticals open the way to the desired baby too.

Transdermal medical preparations available in Czech Republic and basic principles of their application

Andrej Kováčik, Barbora Vraníková

Prakt. lékáren. 2020; 16(2): 97-99 | DOI: 10.36290/lek.2020.016  

Transdermal application allows to administer the drug through the skin with the systemic effect, without the need for the preparation to be swallowed (oral administration) or for the patient to undergo the invasive application of injection (e.g., intravenous administration). Transdermal delivery offers a wide range of benefits; however, their effect may be significantly affected by the improper technique of the application that differs for each preparation. This paper introduces the basic overview of liquid, semi-solid and solid transdermal delivery systems available in Czech Republic with the specific focus on their correct application.

Gastrointestinal problems during travelling - how to prepare and how to deal with them

Kateřina Vašutová, Karel Vašut

Prakt. lékáren. 2020; 16(2): 101-104 | DOI: 10.36290/lek.2020.017  

Digestive problems are a very common complication when traveling. Traveling diarrhea is one of the most common health problems affecting tourists in most countries. Other unpleasant complications are constipation and motion sickness (kinetosis). The pharmacist should be able to advise the traveler about the precautions before traveling and the equipment of the appropriate travel kit.