Čtyři zastavení v ubíhajícím roce

prof. RNDr. Luděk Jahodář, CSc. předseda ČFS

Prakt. lékáren. 2013; 9(6): 211  

Adverse drug effects on the skin

Marie Viktorinová

Prakt. lékáren. 2013; 9(6): 214-218  

The article presents an overview of aetiopathogenetic factors, clinical presentation, diagnosis, and treatment of adverse drug effects on the skin (drug exanthema) that may arise following both internal and external drug administration.

Current treatment of cough

Jan Juřica

Prakt. lékáren. 2013; 9(6): 219-223  

The article reviews current knowledge on drugs and preparations for treatment of dry and mucus-producing cough which are currently available in the Czech Republic. In the introduction, there are given some suggestions concerning frequent and inappropriate combination of antitussive and mucoregulating drugs. The part of the article is denoted to antitussives, with respect to mechanisms of action, pharmacokinetics, and adverse effects of opioid-derived antitussives. Another part reviews the drugs for treatment of mucus-producing cough with respect to categorization according to the major mechanism of action, adverse effects, pharmacokinetics,...

Systemic treatment of psoriasis

Zuzana Nevoralová

Prakt. lékáren. 2013; 9(6): 225-229  

Psoriasis is a chronic, inflammatory hyperproliferative disease of the skin, scalp, nails and joints. It belongs to a group of papulosquamosus skin disorders and is presented by a variety of clinical presentations. Basic treatment is a local therapy. Another treatment option is a phototherapy, first of all PUVA and 311 nm methods. Systemic treatment is reserved for severe cases refractery to standard local therapy and phototherapy and for inicially very severy cases. There are three therapeutics for first line of systemic treatment: acitretin, cyclosporin A and methotrexat. The second line systemic medicaments are biologics; adalimumab, etanercept,...

Toothache from the algesiologist’s perspective

Pavlína Nosková

Prakt. lékáren. 2013; 9(6): 230-233  

Basic rule of toothache treatment is multimodal analgesia. The article refers to combination of analgetics in toothache treatment. It is also interested in problem of tooth neuropatic pain.

Cystic fibrosis and current treatment options

Eliška Tajovská

Prakt. lékáren. 2013; 9(6): 234-239  

Cystic fibrosis (CF) is a serious hereditary disease, which represents a significant burden for patients and their families, and shortens the life of patients. The disease manifests with pulmonary and extrapulmonary manifestations, a characteristic symptom of CF is a high concentration of chloride in the sweat of patients. Mucostasis, obstruction and chronic infection occur in the lungs. Treatment of pulmonary manifestations has a major impact on the quality and length of the life of patients. This is especially good care of the airway through respiratory physiotherapy and drugs that reduce the viscosity of mucus in the airways and in the treatment...

Will be Harpagophytum root source of a well- established drug?

Luděk Jahodář

Prakt. lékáren. 2013; 9(6): 243-246  

Devil´s claw, Harpagophytum procumbens or H. zeyheri, is the element of traditional South African´s herbal medicine. Since 70. years of last century the drug penetrated into European official medicine, the root of the plant is currently the drug of the European Pharmacopoeia. A broad spectrum of therapeutical indications of traditional medicine is verified by modern pharmacognostic and pharmacologic methods including methods of clinical assessment. The definite confirmation of ethnopharmacologically declared anti-inflammatory and analgesic effects demands supplementary studies. EMA Community Monograph evaluated the drug as Traditional herbal...

Correct dosage of paracetamol; analgesic efficacy of paracetamol in combination with caffeine

Lenka Součková

Prakt. lékáren. 2013; 9(6): 240-242  

Paracetamol is currently among the most widely used analgesics worldwide. Many years of experience with the use of paracetamol have shown its excellent tolerability and efficacy in therapeutic doses, which are the main reasons for its frequent prescription and usage both in patients in infancy and toddlerhood and in children of preschool and school age, as well as in adult and geriatric patients, but also pregnant and breast-feeding patients. In a number of countries, paracetamol is among over-the-counter drugs and thus ranks first in the consumption of analgesic-antipyretic drugs in many cases. With the increasing use of paracetamol, however,...

Adverse drug reactions reported to SÚKL in 2012

Eva Jirsová

Prakt. lékáren. 2013; 9(6): 247-249  

Continuous monitoring of drug safety is the scope of pharmacovigilance. Benefit/ risk ratio of each medicinal product is reassessed with every newly detected pharmacovigilance signal with the aim to keep on the market only medicines with treatment benefits highly superior to possible risks. Reporting of adverse drug reactions belongs to most important sources of safety information. In 2012 State institute for drug control received 2 033 reports of adverse drug reactions from the Czech Republic. 1 099 of these were reported directly to SÚKL (876 from physicians, 48 from pharmacists, 85 from other health care professionals), 1 024 reports originated...

41. mezinárodní kongres pro dějiny farmacie

Mgr. Jan Babica

Prakt. lékáren. 2013; 9(6): 249  

Kadaň nás vzorně pohostila aneb vzpomínka na XXIX. Lékárnické dny

PharmDr. Pavel Grodza

Prakt. lékáren. 2013; 9(6): 250  

Beskydské setkání farmaceutických chemiků

prof. PharmDr. Martin Doležal, Ph.D.

Prakt. lékáren. 2013; 9(6): 250  

Autodidaktický test 5/2013

Prakt. lékáren. 2013; 9(6): 251-252  

Autodidaktický test 6/2013

Prakt. lékáren. 2013; 9(6): 253-254