Jaký byl rok 2016 z pohledu člena výboru ČFS?

PharmDr. Pavel Grodza

Prakt. lékáren. 2016; 12(6): 219  

Lipertance® - first fixed triple combination of atorvastatin, perindopril arginine, and amlodipine

Jiří Widimský jr.

Prakt. lékáren. 2016; 12(6): 224-226  

The article briefly introduces a novel fixed triple combination of the hypolipidaemic drug atorvastatin and two antihypertensives: perindopril arginine and amlodipine. Because of the frequent co-occurrence of hypertension and dyslipidaemia, this combination can be of benefit and useful in a large number of patients. The use of this combination can improve compliance with the pharmacological treatment of hypertension and dyslipidaemia.

Nasal corticosteroids in a treatment of rhinosinusitis

Jan Rottenberg

Prakt. lékáren. 2016; 12(6): 227-230 | DOI: 10.36290/lek.2016.055  

Nasal corticosteroids represent the baseline therapy especially in case of chronic rhinosinusitis namely in allergic rhinosinusitis and rhinosinusitis related to nasal polyposis. The active substances available on the market do not vary in terms of efficacy but may considerably vary in terms of side effects. The most common side effects are those related to local nasal mucosa impairment. The adverse reactions related to the level of topical steroids’ bioavailability are rather rare. The publication summarizes basic information about indications, contraindications, adverse effects as well as some practical aspects of treatment by topical...

Pyridoxine use in children with epilepsy: a pharmacist’s point of view

Petra Thomson, Kateřina Ládová

Prakt. lékáren. 2016; 12(6): 232-235 | DOI: 10.36290/lek.2016.056  

Vitamin B6 (pyridoxine) plays a pivotal role in development and functioning of central nervous system. As with other vitamins of the B group, pyridoxine deficiency is rare, but it may occur as a result of some specific genetic disorders of metabolism. This may lead into functional deficiency of vitamin B6 and devolve into pyridoxine-dependent epilepsy in children. Pyridoxin dosing in this indication is based strictly on individual patient’s response and when reeded doses as high as 1g daily are administered orally. Especially with high dose pyridoxine regimens in paediatric population, it is preferable to avoid crushing tablets for administration...

Inonotus obliquuus - active compounds and therapeutic effects

Zdeňka Navrátilová

Prakt. lékáren. 2016; 12(6): 237-239 | DOI: 10.36290/lek.2016.057  

Inonotus obliquus, commonly known as chaga, is a basidiomycetous wood-decaying fungus from Hymenochaetaceae family, growing usually on birch trees. Since the sixteenth century, chaga has been used as a folk medicine in Russia and Northern Europe, mainly for cancer and tuberculosis treatment. Many bioactive compounds were isolated from chaga mushroom, especially polysaccharides, triterpenes and steroids. Nowadays it is used throughout the world and many studies confirm its medicinal effects: anti-tumor, antioxidant, antiinflammatory, hepatoprotective, antimicrobial, immunomodulatory and antidiabetic.

The issue of non-authorised medicinal products

Jana Davidová

Prakt. lékáren. 2016; 12(6): 248-250 | DOI: 10.36290/lek.2016.060  

There are diverse demands influencing the availability of medicinal products. Physicians and patients search for the best available individualised pharmacotherapy. Health care systems as well as medicine producers search for the most effective ways of resource allocation. Those are reasons why, especially in the case of a small market such as Czech Republic, some pharmaceuticals may not be directly available. However, there are ways to acquire such medications. This article describes a legal framework for the use of non-authorised medicinal products in the Czech Republic and some examples from every day practise.

XXXII. lékárnické dny v Kutné Hoře

Prakt. lékáren. 2016; 12(6): 251-252  

Self-medication of common digestive problems

Jana Martinásková

Prakt. lékáren. 2016; 12(6): 240-243 | DOI: 10.36290/lek.2016.058  

Within the self-management of common digestive problems pharmacy provides the first point of contact a pharmacist or pharmaceutical assistant with the patient. Based on the interview with the patient, it is important to choose a suitable product, recommend its proper use and provide information about non-pharmacological and dietary measures, leading to treat indigestion. It is also necessary to consider the recommendation to visit a doctor in case of serious or long-term problems. Article compiles thematically the possibilities of pharmaceutical care of patients with diarrhea, constipation and pyrosis.

Vomiting and diarrhoea in children - how can the pharmacist help?

Hana Kotolová

Prakt. lékáren. 2016; 12(6): 244-247 | DOI: 10.36290/lek.2016.059  

Diarrhoea and vomiting are very frequent symptoms, which we may meet in children. Usually, they are caused by gastrointestinal disorders and have infectional base but they can have many other causes, which are in children specific but less common than in the adults. The base of the therapy of the non-complicated diarrhoea and vomiting is securing of rehydration and following realimentation. From the non-prescription drugs, we can recommend the intestinal adsorbents and probiotics, in older children intestinal disinfectants and in especial cases the analogues of opioids with symptomatic effects as well. Always we get on to the physician, if...

Autodidaktický test 6/16

Prakt. lékáren. 2016; 12(6): 253-254