Z činnosti Spolku moravskoslezských farmaceutů v Ostravě

PharmDr. Pavel Grodza

Prakt. lékáren. 2019; 15(4): 191  

Increasing antibiotic resistance and rational use of antibiotics

Eva Krejčí

Prakt. lékáren. 2019; 15(4): 200-207  

Generally, the term of bacterial resistance refers to the ability of bacteria to survive a specified concentration of a given antibiotic. The current increase in antibiotic resistance is a serious problem, jeopardizing further use of antibiotics for treatment of infections. Resistance to reserve drugs used for serious cases caused by Gram-positive and Gram-negative bacteria (vancomycin, carbapenems) is on a steady increase, recently including also resistance to colistin, being the last antibiotic drug tested as effective against some strains of pseudomonas. Excessive administration of antibiotics leads to elevated incidence of resistant strains (so-called...

Acute and preventive migraine treatment

Andrea Bártková

Prakt. lékáren. 2019; 15(4): 208-212  

Migraine is one of the most common neurological diseases. About one in seven individuals are affected worldwide. With thedevelopment of new knowledge on etiopathogenesis, new treatment options are available.The subject of this talk is a brief overview of acute and preventive migraine treatments available in the Czech Republic.

Current options of treating vulvovaginal discomfort

Tomáš Fait

Prakt. lékáren. 2019; 15(4): 214-216  

Vulvovaginal discomfort is a common complaint in gynaecological patients. More frequently, the cause is dysbacteriosis ratherthan infection. The condition tends to recur. In addition to anti-infective therapy, restoration of the vaginal milieu with probioticsis recommended for both treatment and prevention.

Fixed combination of allopurinol and lesinurad

Pavel Jeremiáš

Prakt. lékáren. 2019; 15(4): 196-199  

The prevalence of hyperuricaemia and gout is rising in the population. To reach target values of uric acid levels, optimal cooperationpatient and doctor is necessary. Along with diet measures, allopurinol from the group of uricostatics is one of the basicestablished drugs. In the indicated cases, it can be advantageously combined with lesinurad, a new preparation of the uricosuricgroup. The advantage of this fixed combination of drugs with a different mechanism of action is, in addition to improved patientcooperation, demonstrable efficacy with a favorable safety profile.

The risk of falls in patients using drugs affecting central nervous system from the perspective of a clinical pharmacist

Jan Vosátka, Josef Malý, Martin Doseděl

Prakt. lékáren. 2019; 15(4): 218-222  

The patient falls occurred at the hospital departments belong among the frequent adverse events that may lead to prolonged hospitalization and increased costs for health-care services. Nowadays, the fall represents one of the quality indicators of provided health-care services, while the motivation to reduce total number of falls as well as their consequences in health-care facilities is increasing. As an effective tool in prevention of drug-related falls might be the presence of clinical pharmacist in a multidisciplinary team, who is capable to implement theoretical knowledge including identification of population fall-risk increasing drugs and to...

Potential therapeutic use of cannabidiol (CBD) from Cannabis sativa

Jana Karlíčková

Prakt. lékáren. 2019; 15(4): 227-230  

The present article informs readers with some terms associated with industrial hemp and so the summary of pharmacologicaleffects of cannabidiol (CBD) is introduced here including several next cannabinoids and their potential for possible use.

Damiana – active compounds and therapeutic effects

Zdeňka Navrátilová

Prakt. lékáren. 2019; 15(4): 231-233  

Turnera diffusa, also known as damiana, is a small shrub from the family Passifloraceae originating from South and Middle America. In traditional medicine, it is used for treatment of many disorders and also as an aphrodisiac. Damiana contains many bioactive compounds, such as flavonoids and other phenolic compounds, monoterpenoids, sesquiterpenoids, steroids, cyanogenic glycosides, alkaloids, and tannins. In vitro studies and animal experiments have shown anxiolytic, antidepressant, antimicrobial, hepatoprotective, antioxidant, antiinflammatory, antidiabetic, gastroprotective, and cytotoxic properties and also some effects on reproductive system....

Mixtures of excipients for extemporanous compounding and possibilities of their use in current pharmaceutical practice

Eva Procházková

Prakt. lékáren. 2019; 15(4): 223-226  

Extemporanous preparation has always been an important part of the services provided by the pharmacy. In modern practice,pharmacies have available range of vehicules produced according to the rules of good manufacturing practice. In this article wefocus on manufactured mixtures of excipients that have appeared in Czech pharmacies in recent years.

The pharmaceutical substances contained in biblical texts of ancient period

Aleš Franc

Prakt. lékáren. 2019; 15(4): 245-248  

This article discusses the ancient drugs for the treatment of various diseases that can be found in the biblical texts of the canonical and deuterocanonical books of the Old and New Testaments. Although the biblical texts – in opposite to sacred books of other religions – are practically not concerned with medicinal products, they contain a number of interesting case reports. What is particularly striking about these examples is that – unlike, for example, Ayurveda, Taoism or primitive shamanism – there is no spiritual significance attributed to these substances. Reason is, that in Jude-Christian philosophy does not exist spiritualization...

The self-treatment of flu nad cold symptoms

Klára Bechná

Prakt. lékáren. 2019; 15(4): 234-241  

Influenza and common colds are infectious diseases affecting all age groups of the population, especially in the colder months ofthe year. Symptoms such as elevated temperature, pain, cough and rhinitis can be observed in both diseases, varying in intensityand character. In uncomplicated cases, the self-treatment of flu and cold symptoms is symptomatic.

Common diseases of the nasal mucosa and their self-healing using OTC medication

Filip Škarda

Prakt. lékáren. 2019; 15(4): 242-244  

An appropriate treatment of nasal mucosa depends very often on the correct specification of the disease agent and right choiceof medicinal product and complementary treatment. The exact incidence of diseases of nasal mucosa is difficult to detect.Rhinitis and similar diseases are one of the most common type of self-healing diseases (only with the help of a pharmacist or apharmaceutical assistant without the intervention of a practitioner or a specialist). In this text I summarize the common diseasesof the nasal mucosa and outline the treatment by using medicine available in the Czech Republic.

Test 4/19

Prakt. lékáren. 2019; 15(4): 249-250