Vitamin C, anti-infective immunity, and problems of deficiency in childrenCurrent pharmacotherapy

Jan Boženský, František Kopřiva, Lucie Kotlářová, Pavel Kostiuk, Zdeněk Procházka, Jiří Slíva

Prakt. lékáren. 2022; 18(1): 27-33 | DOI: 10.36290/lek.2022.004  

Inhalation technique and correct use of inhaler devices in the treatment of asthma bronchiale and chronic obstructive pulmonary disease I. - liquid form inhalersCurrent pharmacotherapy

Veronika Bárková, Dana Mazánková, Karel Vašut

Prakt. lékáren. 2022; 18(1): 21-26 | DOI: 10.36290/lek.2022.003  

The following article deals with aspects of providing pharmaceutical care in patients with asthma bronchiale and chronic obstructive pulmonary disease, for which the pharmacist's knowledge of the correct manipulation technique of inhaler devices is significant. Further, the article presents specific notices to the use of active substances in inhaler form and focuses on the adherence of patients to the treatment using inhalers and its options of support for the patient's treatment by a pharmacist. Furthermore it summarizes all inhalers available on the Czech market containing liquid dosage form (solution and suspension) and for each inhaler presents...

Depression in patients with cardiovascular disease - can be treated safely?Current pharmacotherapy

Eva Kitzlerová

Prakt. lékáren. 2022; 18(1): 14-20  

Depressive disorder is important risk factor for onset and development of cardiovascular diseases. It must be diagnosed and treated early and adequately. Now its evident that depressive symptoms in patients with cardiovascular diseases can be treated effectively and safety and that they can decrease burden of patients with other complications. The first choice of treatment are SSRI antidepressants, but SNRI or other modern antidepressants with specific mechanisms of action can be also used. During the treatment is necessary use the safety dosage of antidepressants, think of individual risk factors for QT prolongation and severe ventricular arrhythmias...

Treatment and diagnostics of cancer in gravidityCurrent pharmacotherapy

Roman Goněc

Prakt. lékáren. 2022; 18(1): 9-13 | DOI: 10.36290/lek.2022.001  

Cancer in pregnancy is rare, and its diagnostics and treatment might brings some challanges. The patient, the fetus, and the course of gravidity should not be put in danger. The pregnancy may make diagnostic both more diffucult and delayed because of its unspecific symptoms. Any procedure has to be carefully discussed, mainly with respect to the stage of gravidity because particular risks are different in the course of gravidity. Not only there are teratogenic effects of drugs and radioation which are most prominent in the first trimester, but there are also interferences with the gravidity or side effects occurring both in the mother and the fetus/newborn....