Hodiny aneb advent v nás

Mgr. Jan Pomykacz

Prakt. lékáren. 2014; 10(6): 203  

Current place of metotrexate in treating rheumatoid arthritis

Radka Svobodová

Prakt. lékáren. 2014; 10(6): 206-210  

Metotrexate (MTX) is currently the most commonly used disease-modifying drug for rheumatoid arthritis. Rheumatoid arthritis (RA) is an inflammatory autoimmune disease characterized by erosive synovitis that ultimately results in joint destruction and disability of the patient. Early diagnosis and initiation of treatment with disease-modifying antirheumatic drugs (DMARDs) has a favourable effect on the disease course. Metotrexate reduces the disease activity and slows down structural joint damage. It is used both as monotherapy and in combination with other DMARDs or with biological drugs. In addition to RA treatment, MTX has been successfully...

Viral warts and their therapy

Helena Aksamítová

Prakt. lékáren. 2014; 10(6): 210-212  

The warts are benign lesions, which occur mainly on the skin, rarely on the mucosa. Human papillomavirus (HPV) is responsible for a number of lesions. Children, adolescents and people with diminished resistence are mostly infected. We differentiate several types of warts – verrucae vulgares, verrucae plantares, verrucae planae juveniles, verrucae filliformes and condylomata accuminata.

Pharmaceutical care of selected diseases of the cardiovascular system in the elderly I.

Stanislava Kalafutová, Božena Jurašková, Josef Malý, Jiří Vlček

Prakt. lékáren. 2014; 10(6): 213-217  

The article deals with the specifics of arterial hypertension in the elderly population and the act of providing pharmaceutical care in pharmacy. In the elderly, there are involution changes in all organ systems, this is a reason why it is necessary to look at the elderly patients individually. Individual approach should be maintained while providing health care and therapy. Pharmacists should be able to assess and highlight potential risks associated with the pharmacotherapy of diseases, and educate the patient about the proper handling and administration of the drugs. Monitoring adverse events is a very important skill of pharmaceutical specialists....

Medicinal plants with a hypnotic and sedative effect

Jan Martin, Denisa Martinová

Prakt. lékáren. 2014; 10(6): 226-229  

Insomnia, especially chronic long-term insomnia is a serious disease. Insomnia significantly reduces quality of life and can lead to many psychological symptoms such as fatigue, sleep and sleepiness during the day, irritability, problems with concentration and memory disorders. In the treatment of insomnia some natural medicines can be used. Among the most effective products are those based on valerian, hops and passionflower.

Current phytotherapeutic options in the treatment of diabetes mellitus

David Koupý, Hana Kotolová, Jana Kučerová

Prakt. lékáren. 2014; 10(6): 229-232  

Diabetes mellitus is a chronic metabolic disease characterized by hyperglycaemia caused either by lowered pancreatic production of insulin or peripheral tissue resistance to its effects. In addition to standard therapeutic strategies such as diet, administration of oral antidiabetic agents or insulin, there are hundreds of medicinal herbs potentially applicable for adjuvant treatment of type 2 diabetes mellitus. The aim of this work is to provide a literature survey of pharmacological effects of herbal drugs contained in tea blends for diabetics, summary of their pharmacologically active substances and evidence of their effects compared with...

Basiscreme DAC − a novel cream basis for extemporaneous preparation, part 2

Jan Hašek

Prakt. lékáren. 2014; 10(6): 221-225  

The second part of the article on Basiscreme DAC (Cremor basalis DAC) cream basis deals with the options of use in extemporaneous formulation in terms of the requirements of Czech prescription. Major attention is paid to topical corticosteroids. Also presented is a comparison with the other hydrocream bases, the properties of which often restrict a more versatile use. Emphasis is also placed on formulations in which there is improper mixing of proprietary medicinal products and where more rational alternatives using active pharmaceutical ingredients are available. anal fissures.

Immunoglobulins and their therapeutical use

Slavomír Strašík

Prakt. lékáren. 2014; 10(6): 233-237  

Immunoglobulins (antibodies) are one of the basic molecules of immune system as a part of specific (acquired) immune answer of organism. Antibodies are produced by plasmatic cells (differentiated B lymfocytes). Wide range of application is determinated especially by their complex mechanism of use and safety profile. Main purpose of this article is rewiev about characteristics and therapeutical use of polyclonal antibodies, although there is an increasing contribution of monoclonal antibodies in modern therapy as well.

Mail-order dispensing of medicinal products - safety medicines from safety sources

Jozef Kolář

Prakt. lékáren. 2014; 10(6): 238-241  

The paper describes the problems of development of mail-order dispensing of medicinal products since it has been established in 2006 in the Czech Republic to the present. The attention is paid to the basic actual national legal regulations and EU legislation.

LVIII. sympozium z dějin farmacie a veterinární medicíny

Martina Lisá

Prakt. lékáren. 2014; 10(6): 212  

Treatment of rhinitis as seen by a pharmacist

Pavel Grodza

Prakt. lékáren. 2014; 10(6): 218-220  

Rhinitis is a common complaint of patients attending the pharmacy. It is necessary to approach to the treatment responsibly, taking into account the patient's history, and then to prescribe a medication or refer the patient to a secondary care physician – an ENT specialist or an allergist. The common infectious viral rhinitis can be treated by a pharmacist or pharmaceutical assistant directly in the particular patient. A wide range of topical agents (nasal drops, sprays, ointments) or systemically administered medicinal products, mostly fixed combinations with antipyretics or antitussives, are available.

Autodidaktický test 6/2014

Prakt. lékáren. 2014; 10(6): 242-243